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MW 358.5 Da, Purity >98%. Induces depolymerisation of cytoplasmic microtubules. Induces a reversible vesiculation of Golgi membranes blocking downstream protein transport. Inhibitor of gap junction communications. Cell-permeable. Anti-inflammatory and anticancer activity.

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Images

Chemical Structure - Ilimaquinone, Cytoplasmic microtubule inhibitor (AB141625), expandable thumbnail

Key facts

CAS number
71678-03-0
Purity
> 98%
Molecular weight
358.5 Da
Molecular formula
C22H30O4
PubChem identifier
72291
Nature
Synthetic

Target data

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MW 358.5 Da, Purity >98%. Induces depolymerisation of cytoplasmic microtubules. Induces a reversible vesiculation of Golgi membranes blocking downstream protein transport. Inhibitor of gap junction communications. Cell-permeable. Anti-inflammatory and anticancer activity.

Key facts

Purity
> 98%
PubChem identifier
72291
Solubility

Soluble in DMSO to 50 mM.

Soluble in ethanol to 50 mM.

Biochemical name
Ilimaquinone
Biological description

Induces depolymerisation of cytoplasmic microtubules. Induces a reversible vesiculation of Golgi membranes blocking downstream protein transport. Inhibitor of gap junction communications. Cell-permeable. Anti-inflammatory and anticancer activity.

Canonical SMILES
CC1CCC2(C(C1(C)CC3=C(C(=O)C=C(C3=O)OC)O)CCCC2=C)C
Isomeric SMILES
C[C@H]1CC[C@]2([C@H]([C@]1(C)CC3=C(C(=O)C=C(C3=O)OC)O)CCCC2=C)C
InChI
InChI=1S/C22H30O4/c1-13-7-6-8-18-21(13,3)10-9-14(2)22(18,4)12-15-19(24)16(23)11-17(26-5)20(15)25/h11,14,18,24H,1,6-10,12H2,2-5H3/t14-,18+,21+,22+/m0/s1
InChIKey
JJWITJNSXCXULM-YVUMSICPSA-N
IUPAC name
3-[[(1R,2S,4aS,8aS)-1,2,4a-trimethyl-5-methylidene-3,4,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl]-2-hydroxy-5-methoxycyclohexa-2,5-diene-1,4-dione

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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1 product image

  • Chemical Structure - Ilimaquinone, Cytoplasmic microtubule inhibitor (ab141625), expandable thumbnail

    Chemical Structure - Ilimaquinone, Cytoplasmic microtubule inhibitor (ab141625)

    2D chemical structure image of ab141625, Ilimaquinone, Cytoplasmic microtubule inhibitor

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Product protocols

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