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MW 184.96 g/mol, Purity >98%. Alkylating agent used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.

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Images

Chemical Structure - Iodoacetamide, Alkylating agent (AB146212), expandable thumbnail

Key facts

CAS number
144-48-9
Purity
> 98%
Form
Solid
Molecular weight
184.96 g/mol
Molecular formula
C2H4INO
Nature
Synthetic

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MW 184.96 g/mol, Purity >98%. Alkylating agent used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.

Key facts

Purity
> 98%
Solubility

Soluble in water to 100 mM.

Biological description

Alkylating agent used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.

IUPAC name
2-Iodoacetamide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - Iodoacetamide, Alkylating agent (ab146212), expandable thumbnail

    Chemical Structure - Iodoacetamide, Alkylating agent (ab146212)

    2D chemical structure image of ab146212, Iodoacetamide, Alkylating agent

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Product protocols

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