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AB146212

Iodoacetamide, Alkylating agent

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MW 184.96 g/mol, Purity >98%. Alkylating agent used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.
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Chemical Structure - Iodoacetamide, Alkylating agent (AB146212)
  • Chemical Structure

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Chemical Structure - Iodoacetamide, Alkylating agent (AB146212)

2D chemical structure image of ab146212, Iodoacetamide, Alkylating agent

Key facts

CAS number

144-48-9

Purity

>98%

Form

Solid

form

Molecular weight

184.96 g/mol

Molecular formula

C<sub>2</sub>H<sub>4</sub>INO

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

Alkylating agent used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.

IUPAC Name

2-Iodoacetamide

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

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