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AB142802

ION NaTRIUM Green™-2 AM, cytosolic Na+ indicator

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(5 Publications)

ION NaTRIUM Green™-2 AM (ING-2 AM) (CAS: 1642554-49-1) (ab142802) is a cell-permeable fluorescent Na+ indicator. Binds to sodium (Kd = 20 mM) and displays excitation/emission maxima of 525 and 545 nm, respectively. MW 1083.9.

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Chemical Structure - ION NaTRIUM Green™-2 AM, cytosolic Na+ indicator (AB142802)
  • Chemical Structure

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Chemical Structure - ION NaTRIUM Green™-2 AM, cytosolic Na+ indicator (AB142802)

2D chemical structure image of ab142802, ION NaTRIUM Green™-2 AM, cytosolic Na+ indicator

Key facts

CAS number

1642554-49-1

Form

Solid

form

Molecular weight

1083.9 Da

Molecular formula

C<sub>5</sub><sub>3</sub>H<sub>6</sub><sub>0</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>1</sub><sub>8</sub>

PubChem

163341954

Nature

Synthetic

Solubility

Soluble in DMSO to 1mg/ml

Biochemical name

Asante NaTRIUM Green-2 AM

Canonical smiles

CC1=CC(=C(C=C1)N2CCOCCN(CCOCCOCC2)C3=C(C=C(C=C3)C4=C5C=C(C(=O)C(=C5OC6=C4C=C(C(=C6Cl)OCOC(=O)C)CCC(=O)OCOC(=O)C)Cl)CCC(=O)OCOC(=O)C)OC)OC

InChi

InChI=1S/C53H60Cl2N2O18/c1-32-7-11-41(43(25-32)64-5)56-15-19-66-20-16-57(18-22-68-24-23-67-21-17-56)42-12-8-36(28-44(42)65-6)47-39-26-37(9-13-45(61)72-29-69-33(2)58)50(63)48(54)52(39)75-53-40(47)27-38(10-14-46(62)73-30-70-34(3)59)51(49(53)55)74-31-71-35(4)60/h7-8,11-12,25-28H,9-10,13-24,29-31H2,1-6H3

IUPAC Name

acetyloxymethyl 3-[3-(acetyloxymethoxy)-7-[3-(acetyloxymethoxy)-3-oxopropyl]-4,5-dichloro-9-[3-methoxy-4-[13-(2-methoxy-4-methylphenyl)-1,4,10-trioxa-7,13-diazacyclopentadec-7-yl]phenyl]-6-oxoxanthen-2-yl]propanoate

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Complementary Products

Biochemicals

AB142806

ION Potassium Green-2 AM, K+ indicator

Chemical Structure - ION Potassium Green-2 AM, K+ indicator (AB142806)

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Biochemicals

AB142803

ION NaTRIUM Green™-2 TMA+ Salt, cytosolic Na+ indicator

Chemical Structure - ION NaTRIUM Green™-2 TMA+ Salt, cytosolic Na+ indicator (AB142803)

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Biochemicals

AB142800

SBFI AM, fluorescent Na+ indicator

Chemical Structure - SBFI AM, fluorescent Na+ indicator (AB142800)

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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Product details

Affinity is 20 mM/34 mM Kd for sodium (absence/presence of K+), and 39 mM (in astrocytes).

Check out our range of Na+ indicator biochemicals here
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

PloS one 16:e0250095 PubMed33891591

2021

Impact of Na+ permeation on collective migration of pulmonary arterial endothelial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Ningyong Xu,Linn Ayers,Viktoriya Pastukh,Mikhail Alexeyev,Troy Stevens,Dhananjay T Tambe

Science advances 7: PubMed33523987

2021

The nuclear piston activates mechanosensitive ion channels to generate cell migration paths in confining microenvironments.

Applications

Unspecified application

Species

Unspecified reactive species

Hong-Pyo Lee,Farid Alisafaei,Kolade Adebawale,Julie Chang,Vivek B Shenoy,Ovijit Chaudhuri

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 54:556-566 PubMed32462850

2020

Fluorometric Na Evaluation in Single Cells Using Flow Cytometry: Comparison with Flame Emission Assay.

Applications

Flow Cyt

Species

Unspecified reactive species

Valentina E Yurinskaya,Nikolay D Aksenov,Alexey V Moshkov,Tatyana S Goryachaya,Alexey A Vereninov

Cancer cell 35:767-781.e6 PubMed31085177

2019

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation.

Applications

Unspecified application

Species

Unspecified reactive species

Mercedes Segovia,Sofia Russo,Mathias Jeldres,Yamil D Mahmoud,Valentina Perez,Maite Duhalde,Pierre Charnet,Matthieu Rousset,Sabina Victoria,Florencia Veigas,Cédric Louvet,Bernard Vanhove,R Andrés Floto,Ignacio Anegon,Maria Cristina Cuturi,M Romina Girotti,Gabriel A Rabinovich,Marcelo Hill

PloS one 14:e0213751 PubMed30856233

2019

Development of a high-throughput fluorescent no-wash sodium influx assay.

Applications

Unspecified application

Species

Unspecified reactive species

Bryan Tay,Teneale A Stewart,Felicity M Davis,Jennifer R Deuis,Irina Vetter
View all publications
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