MW 1128.02 g/mol, Purity >90%.
Cell membrane permeable K+ indicator. Related product (ab142807). APG-2 AM works in cells that have non-specific esterases to hydrolyse the AM to release the dye. Fluorescent probe.
We do not guarantee successful labelling of plant cells; optimisations to allow for loading into plant cells may be required
.
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Publications
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- Nature communications 14:34452023Discovery of senolytics using machine learning.Applications:Unspecified applicationReactive species:Unspecified reactive speciesVanessa Smer-Barreto,Andrea Quintanilla,Richard J R Elliott,John C Dawson,Jiugeng Sun,Víctor M Campa,Álvaro Lorente-Macías,Asier Unciti-Broceta,Neil O Carragher,Juan Carlos Acosta,Diego A OyarzúnPubMed 37301862
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 161:1145022023Dissecting the functions of cancer-associated fibroblasts to therapeutically target head and neck cancer microenvironment.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLlara Prieto-Fernández,Irene Montoro-Jiménez,Beatriz de Luxan-Delgado,María Otero-Rosales,Juan P Rodrigo,Fernando Calvo,Juana M García-Pedrero,Saúl Álvarez-TeijeiroPubMed 37002578
- Frontiers in immunology 14:10902022023Inhibition of sphingosine-1-phosphate receptor 3 suppresses ATP-induced NLRP3 inflammasome activation in macrophages TWIK2-mediated potassium efflux.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYingqin Wang,Chen Wang,Qiaolan He,Guannan Chen,Jie Yu,Jing Cang,Ming ZhongPubMed 36798132
- Frontiers in microbiology 13:9606212022Accumulation patterns of intracellular salts in a new halophilic amoeboflagellate, sp. nov., (Heterolobosea; Discoba) under hypersaline conditions.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHyeon Been Lee,Dong Hyuk Jeong,Jong Soo ParkPubMed 35992684
- Life science alliance 5:2022OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection.Applications:Unspecified applicationReactive species:Unspecified reactive speciesElinor Hortle,Vi Lt Tran,Kathryn Wright,Angela Rm Fontaine,Natalia Pinello,Matthew B O'Rourke,Justin J-L Wong,Philip M Hansbro,Warwick J Britton,Stefan H OehlersPubMed 35545295
- Nature communications 12:23212021Cytoplasmic condensation induced by membrane damage is associated with antibiotic lethality.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFelix Wong,Jonathan M Stokes,Bernardo Cervantes,Sider Penkov,Jens Friedrichs,Lars D Renner,James J CollinsPubMed 33875652
- The Journal of clinical investigation 130:4561-45732020β-Glucan-induced reprogramming of human macrophages inhibits NLRP3 inflammasome activation in cryopyrinopathies.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGiorgio Camilli,Mathieu Bohm,Alícia Corbellini Piffer,Rachel Lavenir,David L Williams,Benedicte Neven,Gilles Grateau,Sophie Georgin-Lavialle,Jessica QuintinPubMed 32716363
- The EMBO journal 38:2019ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGuangming Ren et. al.PubMed 30787184
- Oncotarget 9:12718-127312018Coordinate effects of P2X7 and extracellular acidification in microglial cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPonarulselvam Sekar et. al.PubMed 29560104
Key facts
- CAS number
1369302-24-8
- Purity
> 90%
- Form
Solid
- Molecular weight
1128.02 g/mol
- Nature
Synthetic
- Excitation/Emission
Ex: 526nm, Em: 546nm
Recommended products
MW 1128.02 g/mol, Purity >90%.
Cell membrane permeable K+ indicator. Related product (ab142807). APG-2 AM works in cells that have non-specific esterases to hydrolyse the AM to release the dye. Fluorescent probe.
We do not guarantee successful labelling of plant cells; optimisations to allow for loading into plant cells may be required
.
Key facts
- CAS number
1369302-24-8
- Purity
> 90%
- Form
Solid
- Molecular weight
1128.02 g/mol
- Nature
Synthetic
- Solubility
Soluble in DMSO to 1mg/ml.
- Biological description
Cell membrane permeable K+ indicator. Related product (ab142807). APG-2 AM works in cells that have non-specific esterases to hydrolyse the AM to release the dye. Fluorescent probe.
We do not guarantee successful labelling of plant cells; optimisations to allow for loading into plant cells may be required
- Canonical SMILES
CC(=O)OCOC(=O)CCC6=CC=2C(OC1C(CC(CCC(=O)OCOC(C)=O)C(OCOC(C)=O)C1CL)C=2C3CCC(C(OC)C3)N4CCOCCOCCN(CCOCCOCC4)C5CCC(C)CC5OC)=C(CL)C6=O
- InChI
InChI=1S/C55H64Cl2N2O19/c1-34-7-11-43(45(27-34)66-5)58-15-19-68-23-25-70-21-17-59(18-22-71-26-24-69-20-16-58)44-12-8-38(30-46(44)67-6)49-41-28-39(9-13-47(63)75-31-72-35(2)60)52(65)50(56)54(41)78-55-42(49)29-40(10-14-48(64)76-32-73-36(3)61)53(51(55)57)77-33-74-37(4)62/h7-8,11-12,27-30H,9-10,13-26,31-33H2,1-6H3
- InChIKey
FLNBWSAACUIXPZ-UHFFFAOYSA-N
- Excitation/Emission
Ex: 526nm, Em: 546nm
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
-20°C
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
Notes
ab142806 has low selectivity of Potassium over Sodium and the presence of Sodium will affect results.
Product promise
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Full details and terms and conditions can be found here:
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1 product image
Chemical Structure - ION Potassium Green-2 AM, K+ indicator (ab142806)
2D chemical structure image of ab142806, ION Potassium Green-2 AM, K+ indicator
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Product protocols
- Visit the general protocols
- Visit troubleshooting
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