JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB142806

ION Potassium Green-2 AM, K+ indicator

Be the first to review this product! Submit a review

|

(9 Publications)

MW 1128.02 g/mol, Purity >90%. Cell membrane permeable K+ indicator. Related product (ab142807). APG-2 AM works in cells that have non-specific esterases to hydrolyse the AM to release the dye. Fluorescent probe.
We do not guarantee successful labelling of plant cells; optimisations to allow for loading into plant cells may be required.
1 Images
Chemical Structure - ION Potassium Green-2 AM, K+ indicator (AB142806)
  • Chemical Structure

Lab

Chemical Structure - ION Potassium Green-2 AM, K+ indicator (AB142806)

2D chemical structure image of ab142806, ION Potassium Green-2 AM, K+ indicator

Key facts

CAS number

1369302-24-8

Purity

>90%

Form

Solid

form

Molecular weight

1128.02 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO to 1mg/ml

Biological description

Cell membrane permeable K+ indicator. Related product (ab142807). APG-2 AM works in cells that have non-specific esterases to hydrolyse the AM to release the dye. Fluorescent probe.
We do not guarantee successful labelling of plant cells; optimisations to allow for loading into plant cells may be required.

Canonical smiles

CC(=O)OCOC(=O)CCC6=CC=2C(OC1C(CC(CCC(=O)OCOC(C)=O)C(OCOC(C)=O)C1CL)C=2C3CCC(C(OC)C3)N4CCOCCOCCN(CCOCCOCC4)C5CCC(C)CC5OC)=C(CL)C6=O

InChi

InChI=1S/C55H64Cl2N2O19/c1-34-7-11-43(45(27-34)66-5)58-15-19-68-23-25-70-21-17-59(18-22-71-26-24-69-20-16-58)44-12-8-38(30-46(44)67-6)49-41-28-39(9-13-47(63)75-31-72-35(2)60)52(65)50(56)54(41)78-55-42(49)29-40(10-14-48(64)76-32-73-36(3)61)53(51(55)57)77-33-74-37(4)62/h7-8,11-12,27-30H,9-10,13-26,31-33H2,1-6H3

InChiKey

FLNBWSAACUIXPZ-UHFFFAOYSA-N

Excitation/Emission

Ex: 526nm, Em: 546nm

Product details

ab142806 has low selectivity of Potassium over Sodium and the presence of Sodium will affect results.

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

Publications (9)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 14:3445 PubMed37301862

2023

Discovery of senolytics using machine learning.

Applications

Unspecified application

Species

Unspecified reactive species

Vanessa Smer-Barreto,Andrea Quintanilla,Richard J R Elliott,John C Dawson,Jiugeng Sun,Víctor M Campa,Álvaro Lorente-Macías,Asier Unciti-Broceta,Neil O Carragher,Juan Carlos Acosta,Diego A Oyarzún

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 161:114502 PubMed37002578

2023

Dissecting the functions of cancer-associated fibroblasts to therapeutically target head and neck cancer microenvironment.

Applications

Unspecified application

Species

Unspecified reactive species

Llara Prieto-Fernández,Irene Montoro-Jiménez,Beatriz de Luxan-Delgado,María Otero-Rosales,Juan P Rodrigo,Fernando Calvo,Juana M García-Pedrero,Saúl Álvarez-Teijeiro

Frontiers in immunology 14:1090202 PubMed36798132

2023

Inhibition of sphingosine-1-phosphate receptor 3 suppresses ATP-induced NLRP3 inflammasome activation in macrophages TWIK2-mediated potassium efflux.

Applications

Unspecified application

Species

Unspecified reactive species

Yingqin Wang,Chen Wang,Qiaolan He,Guannan Chen,Jie Yu,Jing Cang,Ming Zhong

Frontiers in microbiology 13:960621 PubMed35992684

2022

Accumulation patterns of intracellular salts in a new halophilic amoeboflagellate, sp. nov., (Heterolobosea; Discoba) under hypersaline conditions.

Applications

Unspecified application

Species

Unspecified reactive species

Hyeon Been Lee,Dong Hyuk Jeong,Jong Soo Park

Life science alliance 5: PubMed35545295

2022

OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection.

Applications

Unspecified application

Species

Unspecified reactive species

Elinor Hortle,Vi Lt Tran,Kathryn Wright,Angela Rm Fontaine,Natalia Pinello,Matthew B O'Rourke,Justin J-L Wong,Philip M Hansbro,Warwick J Britton,Stefan H Oehlers

Nature communications 12:2321 PubMed33875652

2021

Cytoplasmic condensation induced by membrane damage is associated with antibiotic lethality.

Applications

Unspecified application

Species

Unspecified reactive species

Felix Wong,Jonathan M Stokes,Bernardo Cervantes,Sider Penkov,Jens Friedrichs,Lars D Renner,James J Collins

The Journal of clinical investigation 130:4561-4573 PubMed32716363

2020

β-Glucan-induced reprogramming of human macrophages inhibits NLRP3 inflammasome activation in cryopyrinopathies.

Applications

Unspecified application

Species

Unspecified reactive species

Giorgio Camilli,Mathieu Bohm,Alícia Corbellini Piffer,Rachel Lavenir,David L Williams,Benedicte Neven,Gilles Grateau,Sophie Georgin-Lavialle,Jessica Quintin

The EMBO journal 38: PubMed30787184

2019

ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination.

Applications

Unspecified application

Species

Unspecified reactive species

Guangming Ren,Xuanyi Zhang,Yang Xiao,Wen Zhang,Yu Wang,Wenbing Ma,Xiaohan Wang,Pan Song,Lili Lai,Hui Chen,Yiqun Zhan,Jianhong Zhang,Miao Yu,Changhui Ge,Changyan Li,Ronghua Yin,Xiaoming Yang

Oncotarget 9:12718-12731 PubMed29560104

2018

Coordinate effects of P2X7 and extracellular acidification in microglial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Ponarulselvam Sekar,Duen-Yi Huang,Shwu-Fen Chang,Wan-Wan Lin
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com