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MW 364.4 Da, Purity >95%. Cell-permeable Wnt pathway activator. Targets PR72/130 subunit of PP2A. Maintains ESC pluripotency when co-administered with Wnt3a in vitro. Active in vivo.

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Images

Chemical Structure - IQ-1, Wnt pathway activator (AB142079), expandable thumbnail

Key facts

CAS number
331001-62-8
Purity
> 95%
Form
Solid
Molecular weight
364.4 Da
Molecular formula
C21H24N4O2
PubChem identifier
11152734
Nature
Synthetic

Target data

Recommended products

MW 364.4 Da, Purity >95%. Cell-permeable Wnt pathway activator. Targets PR72/130 subunit of PP2A. Maintains ESC pluripotency when co-administered with Wnt3a in vitro. Active in vivo.

Key facts

Purity
> 95%
PubChem identifier
11152734
Biochemical name
isoquinolinylidene)acetaMide
Biological description

Cell-permeable Wnt pathway activator. Targets PR72/130 subunit of PP2A. Maintains ESC pluripotency when co-administered with Wnt3a in vitro. Active in vivo.

Canonical SMILES
CC(=O)C1=CC=C(C=C1)N=NC(C2C3=CC=CC=C3CC(N2)(C)C)C(=O)N
InChI
InChI=1S/C21H24N4O2/c1-13(26)14-8-10-16(11-9-14)24-25-19(20(22)27)18-17-7-5-4-6-15(17)12-21(2,3)23-18/h4-11,18-19,23H,12H2,1-3H3,(H2,22,27)
InChIKey
WQFHCZGUBRVAAW-UHFFFAOYSA-N
IUPAC name
2-[(4-acetylphenyl)diazenyl]-2-(3,3-dimethyl-2,4-dihydro-1H-isoquinolin-1-yl)acetamide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

Notes

This product is manufactured by BioVision, an Abcam company and was previously called 1663 IQ-1. 1663-1 is the same size as the 1 mg size of ab142079.

Product promise

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In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - IQ-1, Wnt pathway activator (ab142079), expandable thumbnail

    Chemical Structure - IQ-1, Wnt pathway activator (ab142079)

    2D chemical structure image of ab142079, IQ-1, Wnt pathway activator

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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