Skip to main content

MW 269.23 Da. Selective JNK3 inhibitor (IC50 values are 390, 360 and 87 nM for JNK1, 2 and 3 respectively). Inhibits JNK phosphorylation and NFκB /AP-1 transcriptional activity. Shows immunosuppressant effects in vivo. .

Be the first to review this product! Submit a review

Images

Chemical Structure - IQ-1S, JNK3 inhibitor (AB146180), expandable thumbnail

Key facts

CAS number
1421610-21-0
Molecular weight
269.23 Da
Molecular formula
C15H8N3NaO
PubChem identifier
72193876
Nature
Synthetic

Target data

Recommended products

MW 269.23 Da. Selective JNK3 inhibitor (IC50 values are 390, 360 and 87 nM for JNK1, 2 and 3 respectively). Inhibits JNK phosphorylation and NFκB /AP-1 transcriptional activity. Shows immunosuppressant effects in vivo. .

Key facts

PubChem identifier
72193876
Solubility

Soluble in DMSO to 5 mM.

Biochemical name
Sodium;N-oxidoindeno[1,2-b]quinoxalin-11-imine
Biological description

Selective JNK3 inhibitor (IC50 values are 390, 360 and 87 nM for JNK1, 2 and 3 respectively). Inhibits JNK phosphorylation and NFκB /AP-1 transcriptional activity. Shows immunosuppressant effects in vivo.

Canonical SMILES
C1=CC=C2C(=C1)C3=NC4=CC=CC=C4N=C3C2=N[O-].[Na+]
Isomeric SMILES
C1=CC=C\2C(=C1)C3=NC4=CC=CC=C4N=C3/C2=N\[O-].[Na+]
IUPAC name
sodium;N-oxidoindeno[1,2-b]quinoxalin-11-imine

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

1 product image

  • Chemical Structure - IQ-1S, JNK3 inhibitor (ab146180), expandable thumbnail

    Chemical Structure - IQ-1S, JNK3 inhibitor (ab146180)

    2D chemical structure image of ab146180, IQ-1S, JNK3 inhibitor

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com