MW 247.72 g/mol, Purity >98%. Non-selective β adrenoceptor agonist. Structurally similar to adrenaline. Stimulates MAPK activation through cAMP dependent kinases (EC50 = 1-3 μM). Systemically active upon subcutaneous administration.
Also available in simple stock solutions (ab146724) - add 1 ml of water to get an exact, ready-to-use concentration.
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Key facts
- CAS number
- 51-30-9
- Purity
- > 98%
- Form
- Solid
- Molecular weight
- 247.72 g/mol
- Molecular formula
- C11H17NO3.HCl
- Nature
- Synthetic
Recommended products
MW 247.72 g/mol, Purity >98%. Non-selective β adrenoceptor agonist. Structurally similar to adrenaline. Stimulates MAPK activation through cAMP dependent kinases (EC50 = 1-3 μM). Systemically active upon subcutaneous administration.
Also available in simple stock solutions (ab146724) - add 1 ml of water to get an exact, ready-to-use concentration.
Key facts
- CAS number
- 51-30-9
- Purity
- > 98%
- Form
- Solid
- Molecular weight
- 247.72 g/mol
- Molecular formula
- C11H17NO3.HCl
- Nature
- Synthetic
- Solubility
Soluble in water to 100 mM.
- Biological description
Non-selective β adrenoceptor agonist. Structurally similar to adrenaline. Stimulates MAPK activation through cAMP dependent kinases (EC50 = 1-3 μM). Systemically active upon subcutaneous administration.
Also available in simple stock solutions (ab146724) - add 1 ml of water to get an exact, ready-to-use concentration.- IUPAC name
- 4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]-1,2-benzenediol hydrochloride
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- Ambient
- Appropriate long-term storage conditions
- Ambient
- Storage information
- The product can be stored for up to 12 months
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2 product images
Chemical Structure - Isoprenaline hydrochloride (Isoproterenol), Non-selective beta adrenoceptor agonist (ab120710)
2D chemical structure image of ab120710, Isoprenaline hydrochloride (Isoproterenol), Non-selective beta adrenoceptor agonist
Functional Studies - Isoprenaline hydrochloride (Isoproterenol), Non-selective beta adrenoceptor agonist (ab120710)
ab62153 staining HSL pSer855 in NIH-3T3 cells treated with isoprenaline hydrochloride (ab120710), by ICC/IF. Increase of HSL pSer855 expression correlates with increased concentration of isoprenaline hydrochloride, as described in literature.
The cells were incubated at 37°C for 30 minutes in media containing different concentrations of ab120710 (isoprenaline hydrochloride) in DMSO, fixed with 4% formaldehyde for 10 minutes at room temperature and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab62153 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 anti-rabbit polyclonal antibody (Goat Anti-Rabbit IgG H&L (DyLight® 488) preadsorbed ab96899) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
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