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AB146410

KNK 437 (Heat Shock Protein Inhibitor I), heat shock protein biosynthesis inhibitor

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MW 245.23 Da, Purity >98%. Selective heat shock protein biosynthesis inhibitor. Induces neurite outgrowth in PC12 cells. Thermosensitizes cancer cells. Inhibits thermotolerance in vivo. .
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Chemical Structure - KNK 437 (Heat Shock Protein Inhibitor I), heat shock protein biosynthesis inhibitor (AB146410)
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Chemical Structure - KNK 437 (Heat Shock Protein Inhibitor I), heat shock protein biosynthesis inhibitor (AB146410)

2D chemical structure image of ab146410, KNK 437 (Heat Shock Protein Inhibitor I), heat shock protein biosynthesis inhibitor

Key facts

CAS number

218924-25-5

Purity

>98%

Form

Solid

form

Molecular weight

245.23 Da

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>1</sub><sub>1</sub>NO<sub>4</sub>

PubChem

24906297

Nature

Synthetic

Solubility

Soluble in DMSO to 50 mM

Biochemical name

CID 24906297

Biological description

Selective heat shock protein biosynthesis inhibitor. Induces neurite outgrowth in PC12 cells. Thermosensitizes cancer cells. Inhibits thermotolerance in vivo.

Canonical smiles

C1CN(C(=O)C1=CC2=CC3=C(C=C2)OCO3)C=O

InChi

InChI=1S/C13H11NO4/c15-7-14-4-3-10(13(14)16)5-9-1-2-11-12(6-9)18-8-17-11/h1-2,5-7H,3-4,8H2

InChiKey

LZGGUFLRKIMBDQ-UHFFFAOYSA-N

IUPAC Name

3-(1,3-benzodioxol-5-ylmethylidene)-2-oxopyrrolidine-1-carbaldehyde

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions
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Product protocols

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