MW 211.15 Da, Purity >99%. Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more..
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- iScience 25:1054672022Conformational state-dependent regulation of GABA receptor diffusion and subsynaptic domains.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZaha Merlaud,Xavier Marques,Marion Russeau,Ursula Saade,Maelys Tostain,Imane Moutkine,Marc Gielen,Pierre-Jean Corringer,Sabine LéviPubMed 36388998
- Cell metabolism 34:1532-1547.e62022Hypothalamic astrocytes control systemic glucose metabolism and energy balance.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDaniela Herrera Moro Chao,Matthew K Kirchner,Cuong Pham,Ewout Foppen,Raphael G P Denis,Julien Castel,Chloe Morel,Enrica Montalban,Rim Hassouna,Linh-Chi Bui,Justine Renault,Christine Mouffle,Cristina García-Cáceres,Matthias H Tschöp,Dongdong Li,Claire Martin,Javier E Stern,Serge H LuquetPubMed 36198294
- Neuron 110:841-856.e62022Make war not love: The neural substrate underlying a state-dependent switch in female social behavior.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMengyu Liu,Dong-Wook Kim,Hongkui Zeng,David J AndersonPubMed 34982958
- Neuron 109:1721-1738.e42021Specific populations of basal ganglia output neurons target distinct brain stem areas while collateralizing throughout the diencephalon.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLauren E McElvain,Yuncong Chen,Jeffrey D Moore,G Stefano Brigidi,Brenda L Bloodgood,Byung Kook Lim,Rui M Costa,David KleinfeldPubMed 33823137
- Neuron 109:1365-1380.e52021Periaqueductal gray/dorsal raphe dopamine neurons contribute to sex differences in pain-related behaviors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWaylin Yu,Dipanwita Pati,Melanie M Pina,Karl T Schmidt,Kristen M Boyt,Avery C Hunker,Larry S Zweifel,Zoe A McElligott,Thomas L KashPubMed 33740416
- Cell 179:713-728.e172019Multimodal Analysis of Cell Types in a Hypothalamic Node Controlling Social Behavior.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDong-Wook Kim,Zizhen Yao,Lucas T Graybuck,Tae Kyung Kim,Thuc Nghi Nguyen,Kimberly A Smith,Olivia Fong,Lynn Yi,Noushin Koulena,Nico Pierson,Sheel Shah,Liching Lo,Allan-Hermann Pool,Yuki Oka,Lior Pachter,Long Cai,Bosiljka Tasic,Hongkui Zeng,David J AndersonPubMed 31626771
- eLife 8:2019The readily-releasable pool dynamically regulates multivesicular release.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJada H Vaden et. al.PubMed 31364987
- eLife 8:2019Complementary networks of cortical somatostatin interneurons enforce layer specific control.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAlexander Naka et. al.PubMed 30883329
- Scientific reports 7:99692017Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFiona A Bull et. al.PubMed 28855588
- Scientific reports 7:30252017Optical mapping of neuronal activity during seizures in zebrafish.Applications:Unspecified applicationReactive species:Unspecified reactive speciesL Turrini,C Fornetto,G Marchetto,M C Müllenbroich,N Tiso,A Vettori,F Resta,A Masi,G Mannaioni,F S Pavone,F VanziPubMed 28596596
Key facts
- CAS number
- 2439-02-3
- Purity
- > 99%
- Form
- Solid
- Molecular weight
- 211.15 Da
- Molecular formula
- C10H6NNaO3
- PubChem identifier
- 52974250
- Nature
- Synthetic
Alternative names
GLUR, Smp_128940
Recommended products
MW 211.15 Da, Purity >99%. Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more..
Key facts
- CAS number
- 2439-02-3
- Purity
- > 99%
- Form
- Solid
- Molecular weight
- 211.15 Da
- Molecular formula
- C10H6NNaO3
- PubChem identifier
- 52974250
- Nature
- Synthetic
- Biochemical name
- Kynurenic acid sodium salt
- Biological description
Endogenous antagonist at ionotropic, glycine and α7 nicotinic receptors. Neuroprotective in vivo.
Soluble in 1 ml water to give specified mM/ml concentration. Find out more.- Canonical SMILES
- C1=CC=C2C(=C1)C(=O)C=C(N2)C(=O)[O-].[Na+]
- InChI
- InChI=1S/C10H7NO3.Na/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9;/h1-5H,(H,11,12)(H,13,14);/q;+1/p-1
- InChIKey
- RCAZGXKUQDXSSK-UHFFFAOYSA-M
- IUPAC name
- sodium;4-oxo-1H-quinoline-2-carboxylate
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- Ambient
- Appropriate long-term storage conditions
- Ambient
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist (ab120256)
2D chemical structure image of ab120256, Kynurenic acid sodium salt, Endogenous ionotropic / nicotinic antagonist
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