L-165,041, PPARdelta agonist

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MW 402.4 Da, Purity >99%. Potent, selective PPARδ agonist (K_i values are 6 and 730 nM for PPARδ and PPARγ, respectively). Various pharmacological activities in vitro and in vivo including antiangiogenic and antiproliferative effects. Weak blood-brain barrier permeability.

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(R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, 1 25 dihydroxyvitamin D3 receptor, 25-dihydroxyvitamin D3 receptor, CP2C9_HUMAN, CPC9, CYP2C, CYP2C10, CYPIIC9, Cytochrome P-450MP, Cytochrome P450 2C9, Cytochrome P450 MP-4, Cytochrome P450 MP-8, Cytochrome P450 PB-1, Cytochrome P450, family 2, subfamily C, polypeptide 9, Deubiquitinating enzyme 1, FAAR, FLJ00280, FLJ00318, FLJ16020, FLJ16733, MGC102720, MGC149605, MGC2237, MGC2452, MGC3931, MGC88320, Member 1, Microsomal monooxygenase, NF-E2-related factor 2, NF2L2_HUMAN, NR1B1, NR1C1, NR1C2, NR1C3, NR1I1, NR2B1, NRF2, NUC1, NUCI, NUCII, Nfe2l2, Nuclear factor, Nuclear factor (erythroid derived 2) like 2, Nuclear factor erythroid 2-related factor 2, Nuclear factor erythroid derived 2 like 2, Nuclear hormone receptor 1, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, Nuclear receptor subfamily 1 group B member 1, Nuclear receptor subfamily 1 group C member 1, Nuclear receptor subfamily 1 group C member 2, Nuclear receptor subfamily 1 group C member 3, Nuclear receptor subfamily 1 group I member 1, Nuclear receptor subfamily 2 group B member 1, Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, OTTHUMP00000020135, OTTHUMP00000022510, OTTHUMP00000197740, OTTHUMP00000197741, P450 MP, P450 PB 1, P450IIC9, PPAR, PPAR-alpha, PPAR-beta, PPAR-delta, PPAR-gamma, PPAR-鑴, PPARA_HUMAN, PPARB, PPARD_HUMAN, PPARG2, PPARG_HUMAN, PPP1R163, Peroxisome proliferative activated receptor alpha, Peroxisome proliferative activated receptor delta, Peroxisome proliferator activated receptor gamma 2, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor beta, Peroxisome proliferator-activated receptor beta (PPAR-beta), Peroxisome proliferator-activated receptor delta, Peroxisome proliferator-activated receptor gamma, Protein phosphatase 1, regulatory subunit 163, RAR, RAR-alpha, RARA_HUMAN, RARalpha1, RXR alpha1, RXRA_HUMAN, Retinoic acid nuclear receptor alpha variant 1, Retinoic acid nuclear receptor alpha variant 2, Retinoic acid receptor RXR-alpha, Retinoic acid receptor alpha, Retinoic acid receptor alpha polypeptide, Retinoid X nuclear receptor alpha, Retinoid X receptor alpha, S-mephenytoin 4-hydroxylase, UBP, UBP1_HUMAN, Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin specific peptidase 1, Ubiquitin specific protease 1, Ubiquitin thioesterase 1, Ubiquitin thiolesterase 1, Ubiquitin-specific-processing protease 1, VDR_HUMAN, Vitamin D (1,25- dihydroxyvitamin D3) receptor, Vitamin D hormone receptor, Vitamin D nuclear receptor variant 1, Vitamin D receptor, Vitamin D3 receptor, Xenobiotic monooxygenase, cytochrome P-450 S-mephenytoin 4-hydroxylase, erythroid derived 2, flavoprotein-linked monooxygenase, hPPAR, hUBP, like 2, nuclear factor erythroid 2 like 2