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AB120596

L-741,626, D2 antagonist

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(2 Publications)

MW 340.85 g/mol, Purity >99%. Potent and selective D2 antagonist (Ki values are 2.4, 100 and 220 nM at D2, D3 and D4 receptors, respectively). Centrally active following in vivo systemic administration.
1 Images
Chemical Structure - L-741,626, D2 antagonist (AB120596)
  • Chemical Structure

Lab

Chemical Structure - L-741,626, D2 antagonist (AB120596)

2D chemical structure image of ab120596, L-741,626, D2 antagonist

Key facts

CAS number

81226-60-0

Purity

>99%

Form

Solid

form

Molecular weight

340.85 g/mol

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 100 mM

Biological description

Potent and selective D2 antagonist (Ki values are 2.4, 100 and 220 nM at D2, D3 and D4 receptors, respectively). Centrally active following in vivo systemic administration.

IUPAC Name

4-(4-Chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Cell reports. Medicine 5:101559 PubMed38744275

2024

The adipose-neural axis is involved in epicardial adipose tissue-related cardiac arrhythmias.

Applications

Unspecified application

Species

Unspecified reactive species

Yubao Fan,Shanshan Huang,Suhua Li,Bingyuan Wu,Qi Zhao,Li Huang,Zhenda Zheng,Xujing Xie,Jia Liu,Weijun Huang,Jiaqi Sun,Xiulong Zhu,Jieming Zhu,Andy Peng Xiang,Weiqiang Li

PloS one 7:e36397 PubMed22570709

2012

Striatal dopamine transmission is subtly modified in human A53Tα-synuclein overexpressing mice.

Applications

Unspecified application

Species

Unspecified reactive species

Nicola J Platt,Suzana Gispert,Georg Auburger,Stephanie J Cragg
View all publications
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