AB120598
L-745870 trihydrochloride, brain penetrant D4 antagonist
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(2 Publications)
MW 436.21 g/mol, Purity >99%. Highly potent and selective D4 antagonist (Ki values are 0.43, 2300 and 960 nM at D4, D3 and D2, respectively). Brain permeable. Inhibits cell death and shows neuroprotective effects.
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- Chemical Structure
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Chemical Structure - L-745870 trihydrochloride, brain penetrant D4 antagonist (AB120598)
2D chemical structure image of ab120598, L-745870 trihydrochloride, brain penetrant D4 antagonist
Properties and storage information
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Publications (2)
Recent publications for all applications. Explore the full list and refine your search
Acta pharmaceutica Sinica. B 12:2429-2442 PubMed35646536
2022
Identification of anthelmintic parbendazole as a therapeutic molecule for HNSCC through connectivity map-based drug repositioning.
Applications
Unspecified application
Species
Unspecified reactive species
Dong Liang,Chen Yu,Zhao Ma,Xingye Yang,Zhenzhen Li,Xuhui Dong,Xiaojun Qin,Lupei Du,Minyong Li
Scientific reports 11:1843 PubMed33469071
2021
Photoperiodic regulation of dopamine signaling regulates seasonal changes in retinal photosensitivity in mice.
Applications
Unspecified application
Species
Unspecified reactive species
Kousuke Okimura,Yusuke Nakane,Taeko Nishiwaki-Ohkawa,Takashi Yoshimura
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