MW 183.1 Da, Purity >99%. Selective group III mGlu agonist. Achieve your results faster with highly validated, pure and trusted compounds.
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- Molecular therapy. Methods & clinical development 30:1-132023Starburst amacrine cells amplify optogenetic visual restoration through gap junctions.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYusaku Katada,Hiromitsu Kunimi,Naho Serizawa,Deokho Lee,Kenta Kobayashi,Kazuno Negishi,Hideyuki Okano,Kenji F Tanaka,Kazuo Tsubota,Toshihide KuriharaPubMed 37324975
- Biology of reproduction 107:916-9272022Glutamate can act as a signaling molecule in mouse preimplantation embryos†.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAlexandra Špirková,Veronika Kovaříková,Zuzana Šefčíková,Jozef Pisko,Martina Kšiňanová,Juraj Koppel,Dušan Fabian,Štefan ČikošPubMed 35746896
- Cell reports 35:1090222021Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJoana Ribeiro,Christopher A Procyk,Emma L West,Michelle O'Hara-Wright,Monica F Martins,Majid Moshtagh Khorasani,Aura Hare,Mark Basche,Milan Fernando,Debbie Goh,Neeraj Jumbo,Matteo Rizzi,Kate Powell,Menahil Tariq,Michel Michaelides,James W B Bainbridge,Alexander J Smith,Rachael A Pearson,Anai Gonzalez-Cordero,Robin R AliPubMed 33882303
- Current biology : CB 29:763-774.e52019Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina.Applications:Unspecified applicationReactive species:Unspecified reactive speciesVíctor Pérez-Fernández et. al.PubMed 30799247
- Nature communications 8:18132017Rods progressively escape saturation to drive visual responses in daylight conditions.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAlexandra Tikidji-Hamburyan,Katja Reinhard,Riccardo Storchi,Johannes Dietter,Hartwig Seitter,Katherine E Davis,Saad Idrees,Marion Mutter,Lauren Walmsley,Robert A Bedford,Marius Ueffing,Petri Ala-Laurila,Timothy M Brown,Robert J Lucas,Thomas A MünchPubMed 29180667
- Nature chemical biology 10:813-52014An allosteric modulator to control endogenous G protein-coupled receptors with light.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSilvia Pittolo et. al.PubMed 25173999
- PloS one 9:e1061482014Step-by-step instructions for retina recordings with perforated multi electrode arrays.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKatja Reinhard et. al.PubMed 25165854
- The Journal of neuroscience : the official journal of the Society for Neuroscience 34:79-942014Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShen Yin,Meredith J Noetzel,Kari A Johnson,Rocio Zamorano,Nidhi Jalan-Sakrikar,Karen J Gregory,P Jeffrey Conn,Colleen M NiswenderPubMed 24381270
- The Journal of neuroscience : the official journal of the Society for Neuroscience 33:18951-652013Alleviating pain hypersensitivity through activation of type 4 metabotropic glutamate receptor.Applications:Unspecified applicationReactive species:Unspecified reactive speciesBruno Vilar,Jérôme Busserolles,Bing Ling,Sophie Laffray,Lauriane Ulmann,Fanny Malhaire,Eric Chapuy,Youssef Aissouni,Monique Etienne,Emmanuel Bourinet,Francine Acher,Jean-Philippe Pin,Alain Eschalier,Cyril GoudetPubMed 24285900
- The Journal of pharmacology and experimental therapeutics 344:624-362012ADX71743, a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7: in vitro and in vivo characterization.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMikhail Kalinichev,Mélanie Rouillier,Francoise Girard,Isabelle Royer-Urios,Bruno Bournique,Terry Finn,Delphine Charvin,Brice Campo,Emmanuel Le Poul,Vincent Mutel,Sonia Poli,Stuart A Neale,Thomas E Salt,Robert LütjensPubMed 23257312
Key facts
- CAS number
- 23052-81-5
- Purity
- > 99%
- Form
- Solid
- Molecular weight
- 183.1 Da
- Molecular formula
- C4H10NO5P
- PubChem identifier
- 179394
- Nature
- Synthetic
Alternative names
FLJ41058, G protein coupled receptor family C group 1 member F, GLUR, GLUR8, GPRC1C, GPRC1D, GPRC1F, GPRC1H, GRM3_HUMAN, GRM4_HUMAN, GRM8_HUMAN, GluR-3, Glutamate metabotropic receptor 3, Glutamate receptor metabotropic 3, Glutamate receptor metabotropic 4, Glutamate receptor metabotropic 6, Glutamate receptor metabotropic 8, MGC126724, MGLUR3, MGLUR6, MGlu3, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 6 precursor, Metabotropic glutamate receptor 8, Smp_128940, mGlu4, mGlu6, mGlu8, mGluR4
Recommended products
MW 183.1 Da, Purity >99%. Selective group III mGlu agonist. Achieve your results faster with highly validated, pure and trusted compounds.
Key facts
- CAS number
- 23052-81-5
- Purity
- > 99%
- Form
- Solid
- Molecular weight
- 183.1 Da
- Molecular formula
- C4H10NO5P
- PubChem identifier
- 179394
- Nature
- Synthetic
- Biochemical name
- (2S)-2-amino-4-phosphonobutanoic acid
- Biological description
Selective group III mGlu agonist.
- Canonical SMILES
- C(CP(=O)(O)O)C(C(=O)O)N
- Isomeric SMILES
- C(CP(=O)(O)O)[C@@H](C(=O)O)N
- InChI
- InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1
- InChIKey
- DDOQBQRIEWHWBT-VKHMYHEASA-N
- IUPAC name
- (2S)-2-amino-4-phosphonobutanoic acid
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
Product promise
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1 product image
Chemical Structure - L-AP4, group III mGlu agonist (ab120002)
2D chemical structure image of ab120002, L-AP4, group III mGlu agonist
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