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AB142412

L-(+)-Chloramphenicol, antibiotic

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MW 323.13 Da, Purity >98%. Broad spectrum antibiotic agent. Binds selectively to A2451 and A2452 residues in the 23S rRNA of the 50S ribosomal subunit. Prevents peptide bond formation and protein chain elongation inhibiting protein biosynthesis. Shows bacteriostatic effects against a wide variety of Gram-positive and Gram-negative bacteria in vivo. Orally active.

View Alternative Names

ERR a, ERR-alpha, ERR1 protein, ERR1_HUMAN, ESRL 1, ESRR A, Estrogen receptor related 1, Estrogen receptor-like 1, Estrogen-related receptor alpha, Estrra, NR3B1, Nuclear receptor subfamily 3 group B member 1, Steroid hormone receptor ERR1, estrogen receptor related receptor alpha, hERR1

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Chemical Structure - L-(+)-Chloramphenicol, antibiotic (AB142412)
  • Chemical Structure

Lab

Chemical Structure - L-(+)-Chloramphenicol, antibiotic (AB142412)

2D chemical structure image of ab142412, L-(+)-Chloramphenicol, antibiotic

Key facts

CAS number

56-75-7

Purity

>98%

Form

Solid

form

Molecular weight

323.13 Da

Molecular formula

C<sub>1</sub><sub>1</sub>H<sub>1</sub><sub>2</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>5</sub>

PubChem

5959

Nature

Synthetic

Biochemical name

Chloramphenicol

Biological description

Broad spectrum antibiotic agent. Binds selectively to A2451 and A2452 residues in the 23S rRNA of the 50S ribosomal subunit. Prevents peptide bond formation and protein chain elongation inhibiting protein biosynthesis. Shows bacteriostatic effects against a wide variety of Gram-positive and Gram-negative bacteria in vivo. Orally active.

Canonical smiles

C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

Isomeric smiles

C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]

InChi

InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

InChiKey

WIIZWVCIJKGZOK-RKDXNWHRSA-N

IUPAC Name

2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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