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AB145861

L-Mimosine, non-protein amino acid

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MW 198.18 g/mol, Purity >98%. Toxic non-protein amino acid originally isolated from Mimosa pudica. Arrests the cell cycle at the G1 phase in PC-3 cells and at the S phase in LNCaP cells, thus attenuating cell proliferation. Blocks cell cycle progression by chelating iron in asynchronous MDA-MB-453 human breast cancer cells. Arrests DNA synthesis by inhibiting deoxyribonucleotide metabolism. Prolyl hydroxylase (PHD) inhibitor stimulating VEGF production, and increasing proangiogenic capacity in dental pulp-derived cells.
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Chemical Structure - L-Mimosine, non-protein amino acid (AB145861)
  • Chemical Structure

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Chemical Structure - L-Mimosine, non-protein amino acid (AB145861)

2D chemical structure image of ab145861, L-Mimosine, non-protein amino acid

Key facts

CAS number

500-44-7

Purity

>98%

Form

Solid

form

Molecular weight

198.18 g/mol

Molecular formula

C<sub>8</sub>H<sub>1</sub><sub>0</sub>N<sub>2</sub>O<sub>4</sub>

Nature

Synthetic

Biological description

Toxic non-protein amino acid originally isolated from Mimosa pudica. Arrests the cell cycle at the G1 phase in PC-3 cells and at the S phase in LNCaP cells, thus attenuating cell proliferation. Blocks cell cycle progression by chelating iron in asynchronous MDA-MB-453 human breast cancer cells. Arrests DNA synthesis by inhibiting deoxyribonucleotide metabolism. Prolyl hydroxylase (PHD) inhibitor stimulating VEGF production, and increasing proangiogenic capacity in dental pulp-derived cells.

IUPAC Name

(S)-2-Amino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)propanoic acid

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months

Product protocols

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