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AB285402

LB-100

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MW 268.31 Da, Purity >98%. LB-100 is a potent protein phosphatase 2A (PP2A) inhibitor with IC₅₀s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.

Key facts

CAS number

1632032-53-1

Purity

>98%

Form

Solid

form

Molecular weight

268.31 Da

Molecular formula

C<sub>1</sub><sub>3</sub>H<sub>2</sub><sub>0</sub>N<sub>2</sub>O<sub>4</sub>

PubChem

45101433

Nature

Synthetic

Solubility

50 mg/ml

Soluble in DMSO

Soluble in water at 50 mg/ml

Biochemical name

7-Oxabicyclo[2.2.1]heptane-2-carboxylic acid, 3-[(4-methyl-1-piperazinyl)carbonyl]-, (1R,4S)-rel-

Biological description

LB-100 is a potent protein phosphatase 2A (PP2A) inhibitor with IC₅₀s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.

Canonical smiles

CN1CCN(CC1)C(=O)C2C3CCC(C2C(=O)O)O3

Isomeric smiles

CN1CCN(CC1)C(=O)C2[C@@H]3CC[C@H](C2C(=O)O)O3

InChi

InChI=1S/C13H20N2O4/c1-14-4-6-15(7-5-14)12(16)10-8-2-3-9(19-8)11(10)13(17)18/h8-11H,2-7H2,1H3,(H,17,18)/t8-,9+,10?,11?/m0/s1

InChiKey

JUQMLSGOTNKJKI-IZUQBHJASA-N

IUPAC Name

(1R,4S)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called B2031 LB-100. B2031-5 is the same size as the 5 mg size of ab285402.

Protect from air and light.

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark|This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
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Product protocols

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