Leflunomide, Immunomodulatory agent

Be the first to review this product! Submit a review

|

(0 Publication)

MW 270.21 Da, Purity >98%. Immunomodulatory agent. Inhibits dihydroorotate dehydrogenase (K_i = 2.7 μM). Inhibits T and B cell activity and prevents lymphocyte cell cycle proliferation and progression. Also shows anti-inflammatory activity. Active In vivo.

View Alternative Names

1,8-cineole 2-exo-monooxygenase, 2410064E05Rik, AHR_HUMAN, AI195561, AI256365, AI838772, AW493413, Ah receptor, Albendazole monooxygenase, Albendazole sulfoxidase, Aromatic hydrocarbon receptor, Aryl hydrocarbon receptor, Aryl hydrocarbon receptor precursor, BXR, C430023I11Rik, CAR, CAR BETA, CARA, CP33, CP34, CP3A4_HUMAN, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIIA3, CYPIIIA4, Car 1, Class E basic helix-loop-helix protein 76, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 subfamily IIIA polypeptide 4, Cytochrome P450-PCN1, DmRab9, FLJ11090, Glucocorticoid inducible P450, HD 7, HD 7B, HD 9, HD protein, HDAC, HDAC 7B, HDAC 9B, HDAC 9FL, HDAC9_HUMAN, HDH, HDRP, HD_HUMAN, HGNC:348, HLP, HUNTINGTON CHOREA, Histone deacetylase 4/5 related protein, Histone deacetylase 7, Histone deacetylase 7B, Histone deacetylase 9, Histone deacetylase 9A, Histone deacetylase-related protein, Huntingtin, Huntington disease protein, Huntington's disease protein homolog, IT 15, KIAA0744, MB67, MEF2 interacting transcription repressor protein, MEF2-interacting transcription repressor MITR, MGC104252, MGC112732, MGC126680, MGC97144, MITR, NF 25, NR1I2_HUMAN, NR1I3_HUMAN, Nifedipine oxidase, Nuclear receptor subfamily 1 group I member 2, Nuclear receptor subfamily 1 group I member 3, ONR 1, OTTHUMP00000215173, OTTHUMP00000215174, OTTHUMP00000215175, OTTMUSP00000026909, Orphan nuclear receptor MB67, Orphan nuclear receptor NR1I3, Orphan nuclear receptor PAR 1, Orphan nuclear receptor PXR, P450 III steroid inducible, P450 PCN1, P450, family III, P450C3, PAR, PAR q, PRR, Pregnane X receptor, Quinine 3-monooxygenase, RAB9 member RAS oncogene family, RAB9A member RAS oncogene family, RAB9A_HUMAN, RAS ASSOCIATED PROTEIN RAB9, RP24-311F12.2, Rab 9, Ras-related protein Rab-9A, SCAN1, SXR, Sid6061p, Sid99, Steroid and xenobiotic receptor, TYDP, TYDP1_HUMAN, Taurochenodeoxycholate 6-alpha-hydroxylase, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1, ZHD, bHLHe76, constitutive active receptor, constitutive androstane nuclear receptor variant 2, constitutive androstane nuclear receptor variant 3, constitutive androstane nuclear receptor variant 4, constitutive androstane nuclear receptor variant 5, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, orphan nuclear hormone receptor, pregnane X nuclear receptor variant 2