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AB120853

Lithium chloride, GSK3beta inhibitor

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(5 Publications)

MW 42.39 g/mol, Purity >99%. Direct, non-competitive GSK3β inhibitor in vitro (Ki = 2 mM). Elicits various neuropharmacological effects.
1 Images
Chemical Structure - Lithium chloride, GSK3beta inhibitor (AB120853)
  • Chemical Structure

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Chemical Structure - Lithium chloride, GSK3beta inhibitor (AB120853)

2D chemical structure image of ab120853, Lithium chloride, GSK3beta inhibitor

Key facts

CAS number

7447-41-8

Purity

>99%

Form

Solid

form

Molecular weight

42.39 g/mol

Molecular formula

LiCl

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

Direct, non-competitive GSK3β inhibitor in vitro (Ki = 2 mM). Elicits various neuropharmacological effects.

IUPAC Name

Lithium chloride

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Complementary Products

Primary Antibodies

AB32391

Anti-GSK3 beta antibody [Y174]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSK3 beta antibody [Y174] (AB32391)

  • 5
  • 2
Biochemicals

AB120225

Harmine, DYRK1A inhibitor

Chemical Structure - Harmine, DYRK1A inhibitor (AB120225)

  • 0
  • 0
Biochemicals

AB120962

SB 415286, GSK3 inhibitor

Chemical Structure - SB 415286, GSK3 inhibitor (AB120962)

  • 0
  • 0
Biochemicals

AB141296

Indirubin-3'-monoxime, GSK3beta inhibitor. CDK inhibitor.

Chemical Structure - Indirubin-3'-monoxime, GSK3beta inhibitor. CDK inhibitor. (AB141296)

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  • 0
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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Product protocols

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 15:7712 PubMed39231947

2024

10-hydroxy-2-decenoic acid prevents osteoarthritis by targeting aspartyl β hydroxylase and inhibiting chondrocyte senescence in male mice preclinically.

Applications

Unspecified application

Species

Unspecified reactive species

Nana Geng,Mengtian Fan,Biao Kuang,Fengmei Zhang,Menglin Xian,Lin Deng,Cheng Chen,Yiming Pan,Jianqiang Chen,Naibo Feng,Li Liang,Yuanlan Ye,Kaiwen Liu,Xiaoli Li,Yu Du,Fengjin Guo

Cell death & disease 14:292 PubMed37185889

2023

Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.

Applications

Unspecified application

Species

Unspecified reactive species

GuoYan Wang,SenLin Qin,Lei Chen,HuiJun Geng,YiNing Zheng,Chao Xia,JunHu Yao,Lu Deng

Drug design, development and therapy 15:245-257 PubMed33519190

2021

Paeoniflorin Sensitizes Breast Cancer Cells to Tamoxifen by Downregulating microRNA-15b via the FOXO1/CCND1/β-Catenin Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Yanhong Wang,Qian Wang,Xibei Li,Gongwen Luo,Mou Shen,Jia Shi,Xueliang Wang,Lu Tang

Journal of the American Heart Association 9:e015686 PubMed32500803

2020

Enhanced Generation of Induced Cardiomyocytes Using a Small-Molecule Cocktail to Overcome Barriers to Cardiac Cellular Reprogramming.

Applications

Unspecified application

Species

Unspecified reactive species

Vivek P Singh,Jaya Pratap Pinnamaneni,Aarthi Pugazenthi,Deepthi Sanagasetti,Megumi Mathison,Kai Wang,Jianchang Yang,Todd K Rosengart

Frontiers in cellular neuroscience 12:16 PubMed29449801

2018

Lithium Inhibits GSK3β and Augments GluN2A Receptor Expression in the Prefrontal Cortex.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah A Monaco,Brielle R Ferguson,Wen-Jun Gao
View all publications
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