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MW 513.5 Da. Peripheral selective μ opioid receptor agonist. Ki values are 3, 48 and 1156 nM for opioid receptor subtypes μ, δ and κ, respectively. High doses allow central μ receptor activation. Antidiarrheal, antipruritic and antihyperalgesic agent.

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Key facts

CAS number
34552-83-5
Form
Liquid
Molecular weight
513.5 Da
Molecular formula
C29H34Cl2N2O2
PubChem identifier
71420
Nature
Synthetic

Target data

Recommended products

MW 513.5 Da. Peripheral selective μ opioid receptor agonist. Ki values are 3, 48 and 1156 nM for opioid receptor subtypes μ, δ and κ, respectively. High doses allow central μ receptor activation. Antidiarrheal, antipruritic and antihyperalgesic agent.

Key facts

PubChem identifier
71420
Biochemical name
Loperamide hydrochloride
Biological description

Peripheral selective μ opioid receptor agonist. Ki values are 3, 48 and 1156 nM for opioid receptor subtypes μ, δ and κ, respectively. High doses allow central μ receptor activation. Antidiarrheal, antipruritic and antihyperalgesic agent.

Canonical SMILES
CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl
InChI
InChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H
InChIKey
PGYPOBZJRVSMDS-UHFFFAOYSA-N
IUPAC name
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C

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