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MW 461 Da, Purity >99%. Selective non-peptide angiotensin II type 1 (AT1) receptor antagonist (Ki = 10 nM). Blocks classical actions of angiotensin II (ab120183). Displays antihypertensive action and downregulates TFG-β regulation. Active *in vivo*.
- CAS number
124750-99-8
- Purity
> 99%
- Form
Solid
- Molecular weight
461 Da
- Molecular formula
C22H22ClKN6O
- PubChem identifier
11751549
- Nature
Synthetic
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MW 461 Da, Purity >99%. Selective non-peptide angiotensin II type 1 (AT1) receptor antagonist (Ki = 10 nM). Blocks classical actions of angiotensin II (ab120183). Displays antihypertensive action and downregulates TFG-β regulation. Active *in vivo*.
Key facts
- CAS number
124750-99-8
- Purity
> 99%
- Form
Solid
- Molecular weight
461 Da
- Molecular formula
C22H22ClKN6O
- PubChem identifier
11751549
- Nature
Synthetic
- Biochemical name
Cozaar
- Biological description
Selective non-peptide angiotensin II type 1 (AT1) receptor antagonist (Ki = 10 nM). Blocks classical actions of angiotensin II (ab120183). Displays antihypertensive action and downregulates TFG-β regulation. Active *in vivo*.
- Canonical SMILES
CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[N-]4)CO)Cl.[K+]
- InChI
InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
- InChIKey
OXCMYAYHXIHQOA-UHFFFAOYSA-N
- IUPAC name
potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
Ambient
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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