AB120594
LP-12 hydrochloride, 5-HT7 agonist
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(1 Publication)
MW 518.13 g/mol, Purity >98%. 5-HT7 agonist. Selective over D2, 5-HT1A and 5-HT2A receptors (Ki values are 0.13, 224, 60.9 and >1000 nM, respectively). Shows pro-nociceptive effect.
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- Chemical Structure
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Chemical Structure - LP-12 hydrochloride, 5-HT7 agonist (AB120594)
2D chemical structure image of ab120594, LP-12 hydrochloride, 5-HT7 agonist
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Properties and storage information
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Publications (1)
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FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37:e22893 PubMed36961387
2023
Serotonin/5-HT7 receptor provides an adaptive signal to enhance pigmentation response to environmental stressors through cAMP-PKA-MAPK, Rab27a/RhoA, and PI3K/AKT signaling pathways.
Applications
Unspecified application
Species
Unspecified reactive species
Hui-Hao Tang,Yi-Fan Zhang,Li-Li Yang,Chen Hong,Kai-Xian Chen,Yi-Ming Li,Hua-Li Wu
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