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AB145310

Lucigenin, Superoxide anion radical chemiluminescent probe

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(2 Publications )

MW 510.5 Da, Purity >98%. Selective superoxide anion radical chemiluminescent probe and fluorescent chloride-sensitive indicator. Generates chemiluminescence in the presence of superoxide (O2-). Detects vascular superoxide formation in vivo..
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Chemical Structure - Lucigenin, Superoxide anion radical chemiluminescent probe (AB145310)
  • Chemical Structure

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Chemical Structure - Lucigenin, Superoxide anion radical chemiluminescent probe (AB145310)

2D chemical structure image of ab145310, Lucigenin, Superoxide anion radical chemiluminescent probe

Key facts

CAS number

2315-97-1

Purity

>98%

Form

Solid

form

Molecular weight

510.5 Da

Molecular formula

C<sub>2</sub><sub>8</sub>H<sub>2</sub><sub>2</sub>N<sub>4</sub>O<sub>6</sub>

PubChem

65099

Nature

Synthetic

Solubility

Soluble in water

Soluble in ethanol to 10 mM

Soluble in DMSO to 25 mM

Biochemical name

Lucigenin

Biological description

Selective superoxide anion radical chemiluminescent probe and fluorescent chloride-sensitive indicator. Generates chemiluminescence in the presence of superoxide (O2-). Detects vascular superoxide formation in vivo.

Canonical smiles

C[N+]1=C2C=CC=CC2=C(C3=CC=CC=C31)C4=C5C=CC=CC5=[N+](C6=CC=CC=C64)C.[N+](=O)([O-])[O-].[N+](=O)([O-])[O-]

InChi

InChI=1S/C28H22N2.2NO3/c1-29-23-15-7-3-11-19(23)27(20-12-4-8-16-24(20)29)28-21-13-5-9-17-25(21)30(2)26-18-10-6-14-22(26)28;2*2-1(3)4/h3-18H,1-2H3;;/q+2;2*-1

InChiKey

KNJDBYZZKAZQNG-UHFFFAOYSA-N

IUPAC Name

10-methyl-9-(10-methylacridin-10-ium-9-yl)acridin-10-ium;dinitrate

Excitation/Emission

Ex: 455nm, Em: 455nm

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Biochemicals

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Biochemicals

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Biochemicals

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Refer to SDS for further information.

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Product protocols

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Redox biology 56:102432 PubMed35981417

2022

Macrophage SAMSN1 protects against sepsis-induced acute lung injury in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Wanli Jiang,Chengtai Ma,Jiawei Bai,Xianjin Du

Frontiers in pharmacology 10:1589 PubMed32116659

2020

Five Constituents in L. Attenuate Palmitic Acid-Induced Hepatocyte Injury Inhibiting the Protein Kinase C-α/Nicotinamide-Adenine Dinucleotide Phosphate Oxidase Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Lishan Zhou,Jianqiao Tang,Xuan Yang,Hui Dong,Xiaoli Xiong,Juan Huang,Linli Zhang,Huan Qin,Suqi Yan
View all publications
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Product promise

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