LY 294002 (DMSO solution), PI3-kinase inhibitor

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MW 307.3 Da, Purity >99%. A highly selective inhibitor of phosphatidylinositol 3-kinase (IC₅₀ = 1.4 μM). Selective over a range of other kinases including protein kinase C, protein kinase A, MAPK and PI4- kinase (IC₅₀ > 50 μM).

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1-phosphatidylinositol 3-kinase, 5 HT 2B receptor, 5 HT(2B), 5 HT2 receptor, 5 Hydroxytryptamine 2C receptor, 5 hydroxytryptamine (serotonin) receptor 2B, 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled, 5 hydroxytryptamine 2B receptor, 5-HT-1C, 5-HT-2, 5-HTR2C, 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, 5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta, 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, 5-bisphosphate 3-kinase catalytic subunit alpha isoform, 5-bisphosphate 3-kinase catalytic subunit beta isoform, 5-bisphosphate 3-kinase catalytic subunit delta isoform, 5-bisphosphate 3-kinase catalytic subunit gamma isoform, 5-ht-1c receptor, 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine 2A receptor, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5HT2A_HUMAN, 5HT2B_HUMAN, 5HT2C_HUMAN, 5HT2F, APDS, C2 PI3K, C2 containing phosphatidylinositol kinase, C2 domain containing alpha polypeptide, CBX, CBX1_HUMAN, CK II, CK II alpha, CK II alpha', CK II beta, CK2A1, CK2A2, CK2B, CK2N, CLOVE, CNK, CPK, CSK21_HUMAN, CSK22_HUMAN, CSK2B_HUMAN, CSNK 2B, CWS5, Casein kinase 2 alpha prime polypeptide, Casein kinase 2 beta polypeptide, Casein kinase II alpha chain, Casein kinase II alpha' chain, Casein kinase II beta subunit, Casein kinase II subunit alpha, Casein kinase II subunit alpha', Casein kinase II subunit beta, Casein kinase II, alpha 1 polypeptide, Casein kinase II, alpha 1 related sequence 4, Cell cycle regulated protein kinase, Chromobox 1, Chromobox homolog 1 (HP1 beta homolog Drosophila ), Chromobox protein homolog 1, Class 2 alpha polypeptide, Cpk m, Csnk2a1-rs4, Cytokine Inducible Kinase, Cytokine-inducible serine/threonine-protein kinase, DKFZp686L193, DKFZp779K1237, DNA PK, DNA-PK catalytic subunit, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, DNPK 1, Drosophila HP1 beta, FGF-inducible kinase, FK506 binding protein 12 rapamycin associated protein 1, FK506 binding protein 12 rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP rapamycin associated protein, FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein 1, FLJ43934, FLJ44809, FNK, FRAP, FRAP1, FRAP2, G5A, GRB 1, GSK-3 beta, GSK3B_HUMAN, GSK3beta isoform, Glycogen synthase kinase-3 beta, HP1 beta, HP1 beta homolog, HP1 beta homolog Drosophila, HP1, Drosophila. homolog of, beta, HP1Hs beta, HTR 2, HTR 2A, HTR2, formerly, HTR2C, HYRC, HYRC 1, Heterochromatin protein 1 beta, Heterochromatin protein 1 homolog beta, Heterochromatin protein p25, Htr 2b, Htr1c, Human heterochromatin protein p25 mRNA complete cds, Hyper radiosensitivity of murine scid mutation, complementing 1, Hyperradiosensitivity complementing 1, mouse, homolog of 1, IMD14, IMD26, Kid 1, Kinase induced by depolarization, M31, MCAP, MCM, MCMTC, MGC102141, MGC133043, MGC138222, MGC138224, MGC142161, MGC142163, MGC142218, MOD 1, MTOR_HUMAN, Mammalian target of rapamycin, Mechanistic target of rapamycin, Modifier 1 protein, NP75 protein, ONCOGENE PIM3, OTTHUMP00000001983, OTTHUMP00000216901, OTTHUMP00000216904, OTTHUMP00000231763, OTTMUSP00000016898;, Oncogene PIM 1, P3C2A_HUMAN, P3C2B_HUMAN, P85A_HUMAN, PI 3 Kinase catalytic subunit alpha, PI 3 Kinase catalytic subunit gamma, PI3 kinase, PI3 kinase p110 subunit alpha, PI3 kinase p110 subunit beta, PI3 kinase p110 subunit delta, PI3 kinase p110 subunit gamma, PI3 kinase p85, PI3 kinase p85 subunit alpha, PI3-K-C2(ALPHA), PI3-K-C2A, PI3-kinase regulatory subunit alpha, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, PI3-kinase subunit p85-alpha, PI3CG, PI3K, PI3K p85, PI3K regulatory subunit alpha, PI3K-C2-alpha, PI3K-C2-beta, PI3K-alpha, PI3K-beta, PI3K-delta, PI3K-gamma, PI3KC A, PI3KCB, PIK3, PIK3C 2A, PIK3C A, PIK3C1, PIK3R1, PIM, PIM1_HUMAN, PIM3_HUMAN, PK3CA_HUMAN, PK3CB_HUMAN, PK3CD_HUMAN, PK3CG_HUMAN, PKRDC, PLK, PLK1_HUMAN, PLK3_HUMAN, PRKDC_HUMAN, PTDINS-3-kinase, PTDINS-3-kinase C2 beta, Phosphatidylinositol 3 kinase catalytic alpha polypeptide, Phosphatidylinositol 3 kinase associated p 85 alpha, Phosphatidylinositol 3 kinase catalytic 110 KD alpha, Phosphatidylinositol 3 kinase catalytic 110 kD gamma, Phosphatidylinositol 3 kinase catalytic beta polypeptide, Phosphatidylinositol 3 kinase catalytic delta polypeptide, Phosphatidylinositol 3 kinase class 2 alpha, Phosphatidylinositol 3 kinase gamma, p110 gamma, Phosphatidylinositol 3 kinase regulatory 1, Phosphatidylinositol 3 kinase, catalytic, gamma polypeptide, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1 (p85 alpha), Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit beta, Phosphatidylinositol 4 5 bisphosphate 3 kinase 110 kDa catalytic subunit gamma, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit alpha isoform, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit beta isoform, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit gamma isoform, Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit alpha, Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta, Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, Phosphatidylinositol-4, Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha, Phosphoinositide 3 kinase B, Phosphoinositide 3 kinase C, Phosphoinositide 3 kinase catalytic alpha polypeptide, Phosphoinositide 3 kinase catalytic beta polypeptide, Phosphoinositide 3 kinase catalytic delta polypeptide, Phosphoinositide 3 kinase class 2 alpha, Phosphoinositide 3 kinase gamma catalytic subunit, Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta, Phosphoinositide 3 kinase, class 2, alpha polypeptide, Phosphoinositide 3 kinase, regulatory subunit 1 (alpha), Phosphoinositide 3-Kinase class 2, beta, Phosphoinositide 3-Kinase-C2-alpha, Phosphoinositide 3-Kinase-C2-beta, Phosphoinositide-3-k, Phosphoinositide-3-kinase catalytic gamma polypeptide, Phosvitin, Pik3cb, Pik3cd, Pik3cg, Pim 1 kinase, Pim 1 oncogene, Pim 3 oncogene, Pim-3 proto-oncogene, serine/threonine kinase, Polo-like kinase 1, Polo-like kinase 3, Proliferation-related kinase, Protein G5a, Protein Kinase DNA Activated Catalytic Polypeptide, Protein kinase Kid 1, Proto-oncogene serine/threonine-protein kinase Pim-1, Proviral integration site 1, Proviral integration site 2, PtdIns 3 kinase p110, PtdIns 3 kinase p85 alpha, PtdIns-3-kinase C2 subunit alpha, PtdIns-3-kinase C2 subunit beta, PtdIns-3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PtdIns-3-kinase subunit alpha, PtdIns-3-kinase subunit beta, PtdIns-3-kinase subunit delta, PtdIns-3-kinase subunit gamma, PtdIns-3-kinase subunit p110-alpha, PtdIns-3-kinase subunit p110-beta, PtdIns-3-kinase subunit p110-delta, PtdIns-3-kinase subunit p110-gamma, RAFT1, RAPT1, RP23-452D3.3, Rapamycin and FKBP12 target 1, Rapamycin associated protein FRAP2, Rapamycin target protein, Rapamycin target protein 1, SEROTONIN 5HT2B RECEPTOR, STPK 13, Serine/threonine kinase Pim 3, Serine/threonine protein kinase PIK3CA, Serine/threonine protein kinase PIK3CG, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase GSK3B, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase PLK3, Serine/threonine-protein kinase Pim-3, Serine/threonine-protein kinase mTOR, Serotonin 5-HT-2C receptor, Serotonin receptor 2A, Serotonin receptor 2B, Serotonin receptor 2C, Stomach fundus serotonin receptor, XRCC 7, caPI3K, chromobox homolog 1, dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1), heterochromatin protein p25 beta, p110 BETA, p110 alpha, p110 gamma, p110D, p110delta, p110dp85a, p120-PI3K, p25beta, p350, p460, p85, p85-ALPHA, phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide, phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta, phosphoinositide-3-kinase, class 2, beta polypeptide, pim 1 kinase 44 kDa isoform, pim 1 oncogene (proviral integration site 1), serotonin 1c receptor, serotonin 2c receptor, serotonin 5-HT-2 receptor, formerly, serotonin 5-HT-2A receptor