JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB120956

LY 303511 dihydrochloride, Negative control for LY 294002

Be the first to review this product! Submit a review

|

(1 Publication)

MW 379.29 g/mol, Purity >98%. Negative control for LY 294002 (ab120243). PI3K inhibitory activity. Inhibits voltage-gated Kv channel activity (IC50 = 64.6 μM). Various pharmacological effects including inhibition of LPS-stimulated FPR1 expression and induction of H2O2 production.
1 Images
Chemical Structure - LY 303511 dihydrochloride, Negative control for LY 294002 (AB120956)
  • Chemical Structure

Lab

Chemical Structure - LY 303511 dihydrochloride, Negative control for LY 294002 (AB120956)

2D chemical structure image of ab120956, LY 303511 dihydrochloride, Negative control for LY 294002

Key facts

CAS number

154447-38-8

Purity

>98%

Form

Solid

form

Molecular weight

379.29 g/mol

Molecular formula

C<sub>1</sub><sub>9</sub>H<sub>1</sub><sub>8</sub>N<sub>2</sub>O<sub>2</sub>.<sub>2</sub>HCl

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Soluble in ethanol to 100 mM

Soluble in 1 eq. HCl to 100 mM

Biological description

Negative control for LY 294002 (ab120243). PI3K inhibitory activity. Inhibits voltage-gated Kv channel activity (IC50 = 64.6 μM). Various pharmacological effects including inhibition of LPS-stimulated FPR1 expression and induction of H2O2 production.

Canonical smiles

CL.CL.O=C2C=C(OC1C(CCCC12)C3CCCCC3)N4CCNCC4

InChi

InChI=1S/C19H18N2O2.2ClH/c22-17-13-18(21-11-9-20-10-12-21)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14;;/h1-8,13,20H,9-12H2;2*1H

InChiKey

GUISTZFSXPSDQO-UHFFFAOYSA-N

IUPAC Name

8-Phenyl-2-(1-piperazinyl)-4H-1-benzopyran-4-one dihydrochloride

style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Free radical biology & medicine 120:228-238 PubMed29559323

2018

Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Hailong Li,Zhongyuan Tang,Peng Chu,Yanlin Song,Ying Yang,Bin Sun,Mengyue Niu,Eskandar Qaed,Abdullah Shopit,Guozhu Han,Xiaodong Ma,Jinyong Peng,Min Hu,Zeyao Tang
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Biochemicals

AB120243

LY 294002, PI3-kinase inhibitor

Western blot - LY 294002, PI3-kinase inhibitor (AB120243)

  • 0
  • 0
Proteins & Peptides

AB7403

Streptavidin (HRP)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Streptavidin (HRP) (AB7403)

  • 5
  • 7
Biochemicals

AB141924

Cytarabine, Pyrimidine nucleoside analog

Chemical Structure - Cytarabine, Pyrimidine nucleoside analog (AB141924)

  • 0
  • 0
Proteins & Peptides

AB128447

Recombinant Human UBE2M/UBC12 protein

SDS-PAGE - Recombinant Human UBE2M/UBC12 protein (AB128447)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com