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MW 250.25 Da, Purity >98%. Soluble guanylate cyclase inhibitor (IC50 = 2 μM). Competitive NADPH inhibitor (Ki = 2 μM). Noncompetitive glutathione reductase inhibitor (Ki = 3 μM). Inhibits leukotriene synthesis (IC50 = 1.8 μM). Selective MPS1 protein kinase inhibitor. Induces p21. Lowers cGMP and cAMP levels in vivo. .
Alternative names=AI838772, AW493413, FLJ11090, MGC104252, MGC112732, RP24-311F12.2, SCAN1, TYDP, TYDP1_HUMAN, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1
- CAS number
91300-60-6
- Purity
> 98%
- Form
Solid
- Molecular weight
250.25 Da
- Molecular formula
C15H10N2O2
- PubChem identifier
3976
- Nature
Synthetic
Recommended products
MW 250.25 Da, Purity >98%. Soluble guanylate cyclase inhibitor (IC50 = 2 μM). Competitive NADPH inhibitor (Ki = 2 μM). Noncompetitive glutathione reductase inhibitor (Ki = 3 μM). Inhibits leukotriene synthesis (IC50 = 1.8 μM). Selective MPS1 protein kinase inhibitor. Induces p21. Lowers cGMP and cAMP levels in vivo. .
Alternative names=AI838772, AW493413, FLJ11090, MGC104252, MGC112732, RP24-311F12.2, SCAN1, TYDP, TYDP1_HUMAN, Tyr-DNA phosphodiesterase 1, Tyrosyl-DNA phosphodiesterase 1
Key facts
- CAS number
91300-60-6
- Purity
> 98%
- Form
Solid
- Molecular weight
250.25 Da
- Molecular formula
C15H10N2O2
- PubChem identifier
3976
- Nature
Synthetic
- Biochemical name
6-Anilino-5,8-quinolinedione
- Biological description
Soluble guanylate cyclase inhibitor (IC50 = 2 μM). Competitive NADPH inhibitor (Ki = 2 μM). Noncompetitive glutathione reductase inhibitor (Ki = 3 μM). Inhibits leukotriene synthesis (IC50 = 1.8 μM). Selective MPS1 protein kinase inhibitor. Induces p21. Lowers cGMP and cAMP levels in vivo.
- Canonical SMILES
C1=CC=C(C=C1)NC2=CC(=O)C3=C(C2=O)C=CC=N3
- InChI
InChI=1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H
- InChIKey
GXIJYWUWLNHKNW-UHFFFAOYSA-N
- IUPAC name
6-anilinoquinoline-5,8-dione
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
-20°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
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