JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB146758

Mant-GTPgammaS (aqueous solution), adenylyl cyclase inhibitor

Be the first to review this product! Submit a review

|

(1 Publication)

MW 672.39 g/mol, Purity >90%. Potent, competitive adenylyl cyclase inhibitor. Fluorescent GTP-γ-S (ab146662) derivative. eIF5B substrate. Noncompetitively inhibits GTP-γ-S-stimulated adenylyl cyclase in Galpha(s)-expressing Sf9 insect cell membranes.
1 Images
Chemical Structure - Mant-GTPgammaS (aqueous solution), adenylyl cyclase inhibitor (AB146758)
  • Chemical Structure

Lab

Chemical Structure - Mant-GTPgammaS (aqueous solution), adenylyl cyclase inhibitor (AB146758)

2D chemical structure image of ab146758, Mant-GTPgammaS (aqueous solution), adenylyl cyclase inhibitor

Key facts

CAS number

136749-24-1

Purity

>90% HPLC

Form

Liquid

form

Molecular weight

672.39 g/mol

Molecular formula

C<sub>1</sub><sub>8</sub>H<sub>2</sub><sub>3</sub>N<sub>6</sub>O<sub>1</sub><sub>4</sub>P<sub>3</sub>S

Nature

Synthetic

Biological description

Potent, competitive adenylyl cyclase inhibitor. Fluorescent GTP-γ-S (ab146662) derivative. eIF5B substrate. Noncompetitively inhibits GTP-γ-S-stimulated adenylyl cyclase in Galpha(s)-expressing Sf9 insect cell membranes.

Excitation/Emission

Ex: 355nm, Em: 448nm

10 mM
style
left-column

Complementary Products

Primary Antibodies

AB24373

Anti-FKBP12 antibody

KO Validated

Western blot - Anti-FKBP12 antibody (AB24373)

  • 5
  • 4
Biochemicals

AB146529

Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate

Chemical Structure - Guanosine 5'-diphosphate [GDP] disodium salt, Nucleoside diphosphate (AB146529)

  • 0
  • 0
Biochemicals

AB144622

ML-SA1, TRPML agonist

Chemical Structure - ML-SA1, TRPML agonist (AB144622)

  • 0
  • 0
Biochemicals

AB142177

ML130, NOD1 inhibitor

Chemical Structure - ML130, NOD1 inhibitor (AB142177)

  • 0
  • 0
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

|

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

style
left-column
style
left-column
style
left-column

Product protocols

style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Developmental cell 42:22-36.e12 PubMed28625565

2017

The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.

Applications

Unspecified application

Species

Unspecified reactive species

Tomoharu Kanie,Keene Louis Abbott,Nancie Ann Mooney,Edward Douglas Plowey,Janos Demeter,Peter Kent Jackson
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com