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MW 215.76 Da, Purity >98%. Antagonist at the NMDA receptor. Acts as a fast, voltage-dependent, open channel NMDA receptor blocker. Used in the clinic to treat Alzheimer's disease. Cognitive enhancer and anxiolytic in vivo.
Alternative names=AMPA 1, AMPA-selective glutamate receptor 1, EPND, FESD, GLUH1, GRIA1_HUMAN, GRIN 2A, GluA1, GluN1, GluN2A, GluR-1, GluR-A, GluR-K1, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit zeta-1, Glutamate receptor, Glutamate receptor 1, Glutamate receptor ionotropic, Glutamate receptor ionotropic AMPA 1, Glutamate receptor ionotropic N methyl D aspartate 1, Glutamate receptor ionotropic N methyl D aspartate 2A, Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1, HBGR1, LKS, MGC133252, MRD8, N methyl D aspartate receptor channel subunit zeta 1, N methyl D aspartate receptor channel, subunit epsilon 1, N methyl D aspartate receptor subunit 2A, N-methyl D-aspartate receptor subtype 2A, N-methyl-D-aspartate receptor, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, NMDA 1, NMDA receptor 1, NMDA receptor subtype 2A, NMDAR, NMDE1_HUMAN, NMDZ1_HUMAN, NR1, NR2A, OTTHUMP00000160135, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000174531, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243, glutamate receptor ionotropic, NMDA 1, hNR2A
- CAS number
41100-52-1
- Purity
> 98%
- Form
Solid
- Molecular weight
215.76 Da
- Molecular formula
C12H22ClN
- PubChem identifier
181458
- Nature
Synthetic
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MW 215.76 Da, Purity >98%. Antagonist at the NMDA receptor. Acts as a fast, voltage-dependent, open channel NMDA receptor blocker. Used in the clinic to treat Alzheimer's disease. Cognitive enhancer and anxiolytic in vivo.
Alternative names=AMPA 1, AMPA-selective glutamate receptor 1, EPND, FESD, GLUH1, GRIA1_HUMAN, GRIN 2A, GluA1, GluN1, GluN2A, GluR-1, GluR-A, GluR-K1, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit zeta-1, Glutamate receptor, Glutamate receptor 1, Glutamate receptor ionotropic, Glutamate receptor ionotropic AMPA 1, Glutamate receptor ionotropic N methyl D aspartate 1, Glutamate receptor ionotropic N methyl D aspartate 2A, Glutamate receptor ionotropic, N-methyl-D aspartate, subunit 1, HBGR1, LKS, MGC133252, MRD8, N methyl D aspartate receptor channel subunit zeta 1, N methyl D aspartate receptor channel, subunit epsilon 1, N methyl D aspartate receptor subunit 2A, N-methyl D-aspartate receptor subtype 2A, N-methyl-D-aspartate receptor, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, NMDA 1, NMDA receptor 1, NMDA receptor subtype 2A, NMDAR, NMDE1_HUMAN, NMDZ1_HUMAN, NR1, NR2A, OTTHUMP00000160135, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000174531, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243, glutamate receptor ionotropic, NMDA 1, hNR2A
Key facts
- CAS number
41100-52-1
- Purity
> 98%
- Form
Solid
- Molecular weight
215.76 Da
- Molecular formula
C12H22ClN
- PubChem identifier
181458
- Nature
Synthetic
- Biochemical name
Memantine hydrochloride
- Biological description
Antagonist at the NMDA receptor. Acts as a fast, voltage-dependent, open channel NMDA receptor blocker. Used in the clinic to treat Alzheimer's disease. Cognitive enhancer and anxiolytic in vivo.
- Canonical SMILES
CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl
- InChI
InChI=1S/C12H21N.ClH/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10;/h9H,3-8,13H2,1-2H3;1H
- InChIKey
LDDHMLJTFXJGPI-UHFFFAOYSA-N
- IUPAC name
3,5-dimethyladamantan-1-amine;hydrochloride
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
Ambient
- Storage information
The product can be stored for up to 12 months
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