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AB141322

Mercaptoethylguanidine (MEG) dihydrobromide, iNOS inhibitor; peroxynitrite scavenger

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(1 Publication)

MW 281.01 g/mol. Selective iNOS inhibitor. Anti-inflammatory properties including direct inhibition of COX activity and potent scavenging of hydroxyl radicals and peroxynitrite. Active in vivo.
1 Images
Chemical Structure - Mercaptoethylguanidine (MEG) dihydrobromide, iNOS inhibitor; peroxynitrite scavenger (AB141322)
  • Chemical Structure

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Chemical Structure - Mercaptoethylguanidine (MEG) dihydrobromide, iNOS inhibitor; peroxynitrite scavenger (AB141322)

2D chemical structure image of ab141322, Mercaptoethylguanidine (MEG) dihydrobromide, iNOS inhibitor; peroxynitrite scavenger

Key facts

CAS number

32665-11-5

Form

Solid

form

Molecular weight

281.01 g/mol

Molecular formula

C<sub>3</sub>H<sub>9</sub>N<sub>3</sub>S.<sub>2</sub>HBr

Nature

Synthetic

Solubility

Soluble in water to 100 mM

Biological description

Selective iNOS inhibitor. Anti-inflammatory properties including direct inhibition of COX activity and potent scavenging of hydroxyl radicals and peroxynitrite. Active in vivo.

Canonical smiles

BR.BR.N=C(N)NCCS

InChi

InChI=1S/C3H9N3S.2BrH/c4-3(5)6-1-2-7;;/h7H,1-2H2,(H4,4,5,6);2*1H

InChiKey

KFDRKDSAUNIOQJ-UHFFFAOYSA-N

IUPAC Name

N-(2-Mercaptoethyl)guanidine dihydrobromide

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of neuroinflammation 15:118 PubMed29678206

2018

Biliverdin reductase-A attenuated GMH-induced inflammatory response in the spleen by inhibiting toll-like receptor-4 through eNOS/NO pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yiting Zhang,Yan Ding,Tai Lu,Yixin Zhang,Ningbo Xu,Devin W McBride,Jiping Tang,John H Zhang
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