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AB146725

Metformin hydrochloride (mM/ml), AMPK activator

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(3 Publications)

MW 165.63 g/mol, Purity >99%. AMPK activator. Antidiabetic and anticancer activity in vivo. Rapidly crosses the blood-brain barrier.

Key facts

CAS number

1115-70-4

Purity

>99%

Form

Solid

form

Molecular weight

165.63 g/mol

Molecular formula

C<sub>4</sub>H<sub>1</sub><sub>1</sub>N<sub>5</sub>.HCl

Nature

Synthetic

Solubility

Soluble in 1 ml water to give specified mM/ml concentration

Biological description

AMPK activator. Antidiabetic and anticancer activity in vivo. Rapidly crosses the blood-brain barrier.

IUPAC Name

N,N-Dimethylimidodicarbonimidic diamide hydrochloride

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Complementary Products

Biochemicals

AB120847

Metformin hydrochloride, AMPK activator

Chemical Structure - Metformin hydrochloride, AMPK activator (AB120847)

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Biochemicals

AB146713

AICAR (Acadesine/AICA riboside) (mM/ml), AMP-activated protein kinase activator

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Biochemicals

AB120746

Sodium salicylate, anti-inflammatory agent

Functional Studies - Sodium salicylate, anti-inflammatory agent (AB120746)

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Sample Prep & Detection Kits

AB193970

Extraction Buffer 5X PTR

SimpleStep

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
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Product protocols

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Gastroenterology 161:653-668.e16 PubMed33915173

2021

TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.

Applications

Unspecified application

Species

Unspecified reactive species

Michael Eyres,Simone Lanfredini,Haonan Xu,Adam Burns,Andrew Blake,Frances Willenbrock,Robert Goldin,Daniel Hughes,Sophie Hughes,Asmita Thapa,Dimitris Vavoulis,Aline Hubert,Zenobia D'Costa,Ahmad Sabbagh,Aswin G Abraham,Christine Blancher,Stephanie Jones,Clare Verrill,Michael Silva,Zahir Soonawalla,Timothy Maughan,Anna Schuh,Somnath Mukherjee,Eric O'Neill

Scientific reports 8:14770 PubMed30282977

2018

Nuclear expansion and pore opening are instant signs of neuronal hypoxia and can identify poorly fixed brains.

Applications

Unspecified application

Species

Unspecified reactive species

Anisa Dehghani,Hulya Karatas,Alp Can,Esra Erdemli,Muge Yemisci,Emine Eren-Kocak,Turgay Dalkara

Oncotarget 9:31473-31489 PubMed30140384

2018

Combination of electroporation delivered metabolic modulators with low-dose chemotherapy in osteosarcoma.

Applications

Unspecified application

Species

Unspecified reactive species

Kheshwant S Gill,Philana Fernandes,Brian Bird,Declan M Soden,Patrick F Forde
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