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MW 183.16 Da, Purity >99%. Novel, nontoxic and selective p53 inducer. Antitumor agent. Promotes tumor cell apoptosis in a mutant p53-dependent manner (IC50 = 10 μM) and prolongs survival. Active in vivo and in vitro.

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Images

Chemical Structure - MIRA-1, p53 inducer (AB145862), expandable thumbnail

Key facts

CAS number
72835-26-8
Purity
> 99%
Form
Solid
Molecular weight
183.16 Da
Molecular formula
C8H9NO4
PubChem identifier
227681
Nature
Synthetic

Target data

Alternative names

AHDC, ALDC, ALDH 1, ALDH 11, ALDH class 1, ALDH class 2, ALDH-E1, ALDH-E2, ALDHI, ALDM, ALHDII, Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase 2, Aldehyde dehydrogenase 1, Aldehyde dehydrogenase 1 family member A1, Aldehyde dehydrogenase 1 soluble, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase 2 family, Aldehyde dehydrogenase 2 family (mitochondrial), Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase liver cytosolic, Aldehyde dehydrogenase mitochondrial, Aldh, DKFZp686C2056, DNA helicase, DNA helicase, RecQ like type 3, Exonuclease WRN, HGNC 12791, Liver mitochondrial ALDH, MGC1806, MGC2318, Mitochondrial aldehyde dehydrogenase 2, Nucleus encoded mitochondrial aldehyde dehydrogenase 2, OTTHUMP00000225301, PUMB 1, RALDH 1, RECQL 2, RECQL 3, RecQ protein-like 2, RecQ-like type 3, RecQ3, Retinal dehydrogenase 1, Retinaldehyde dehydrogenase 1, WRN_HUMAN, Werner syndrome ATP-dependent helicase, Werner syndrome helicase, Werner syndrome protein, Werner syndrome, RecQ helicase like

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MW 183.16 Da, Purity >99%. Novel, nontoxic and selective p53 inducer. Antitumor agent. Promotes tumor cell apoptosis in a mutant p53-dependent manner (IC50 = 10 μM) and prolongs survival. Active in vivo and in vitro.

Key facts

Purity
> 99%
PubChem identifier
227681
Solubility

Soluble in water to 100 mM,.

Soluble in ethanol to 100 mM.

Soluble in DMSO to 100 mM.

Biochemical name
(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate
Biological description

Novel, nontoxic and selective p53 inducer. Antitumor agent. Promotes tumor cell apoptosis in a mutant p53-dependent manner (IC50 = 10 μM) and prolongs survival. Active in vivo and in vitro.

Canonical SMILES
CCC(=O)OCN1C(=O)C=CC1=O
InChI
InChI=1S/C8H9NO4/c1-2-8(12)13-5-9-6(10)3-4-7(9)11/h3-4H,2,5H2,1H3
InChIKey
YXEWPGYLMHXLPS-UHFFFAOYSA-N
IUPAC name
(2,5-dioxopyrrol-1-yl)methyl propanoate

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - MIRA-1, p53 inducer (ab145862), expandable thumbnail

    Chemical Structure - MIRA-1, p53 inducer (ab145862)

    2D chemical structure image of ab145862, MIRA-1, p53 inducer

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Product protocols

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