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AB145862

MIRA-1, p53 inducer

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MW 183.16 Da, Purity >99%. Novel, nontoxic and selective p53 inducer. Antitumor agent. Promotes tumor cell apoptosis in a mutant p53-dependent manner (IC50 = 10 μM) and prolongs survival. Active in vivo and in vitro.

View Alternative Names

AHDC, ALDC, ALDH 1, ALDH 11, ALDH class 1, ALDH class 2, ALDH-E1, ALDH-E2, ALDHI, ALDM, ALHDII, Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase 2, Aldehyde dehydrogenase 1, Aldehyde dehydrogenase 1 family member A1, Aldehyde dehydrogenase 1 soluble, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase 2 family, Aldehyde dehydrogenase 2 family (mitochondrial), Aldehyde dehydrogenase cytosolic, Aldehyde dehydrogenase liver cytosolic, Aldehyde dehydrogenase mitochondrial, Aldh, DKFZp686C2056, DNA helicase, DNA helicase, RecQ like type 3, Exonuclease WRN, HGNC 12791, Liver mitochondrial ALDH, MGC1806, MGC2318, Mitochondrial aldehyde dehydrogenase 2, Nucleus encoded mitochondrial aldehyde dehydrogenase 2, OTTHUMP00000225301, PUMB 1, RALDH 1, RECQL 2, RECQL 3, RecQ protein-like 2, RecQ-like type 3, RecQ3, Retinal dehydrogenase 1, Retinaldehyde dehydrogenase 1, WRN_HUMAN, Werner syndrome ATP-dependent helicase, Werner syndrome helicase, Werner syndrome protein, Werner syndrome, RecQ helicase like

1 Images
Chemical Structure - MIRA-1, p53 inducer (AB145862)
  • Chemical Structure

Lab

Chemical Structure - MIRA-1, p53 inducer (AB145862)

2D chemical structure image of ab145862, MIRA-1, p53 inducer

Key facts

CAS number

72835-26-8

Purity

>99%

Form

Solid

form

Molecular weight

183.16 Da

Molecular formula

C<sub>8</sub>H<sub>9</sub>NO<sub>4</sub>

PubChem

227681

Nature

Synthetic

Solubility

Soluble in water to 100 mM,

Soluble in ethanol to 100 mM

Soluble in DMSO to 100 mM

Biochemical name

(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate

Biological description

Novel, nontoxic and selective p53 inducer. Antitumor agent. Promotes tumor cell apoptosis in a mutant p53-dependent manner (IC50 = 10 μM) and prolongs survival. Active in vivo and in vitro.

Canonical smiles

CCC(=O)OCN1C(=O)C=CC1=O

InChi

InChI=1S/C8H9NO4/c1-2-8(12)13-5-9-6(10)3-4-7(9)11/h3-4H,2,5H2,1H3

InChiKey

YXEWPGYLMHXLPS-UHFFFAOYSA-N

IUPAC Name

(2,5-dioxopyrrol-1-yl)methyl propanoate

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

Product protocols

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