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MW 220.25 Da, Purity >99%. Mre11-Rad50-Nbs1 (MRN)-ATM complex inhibitor that blocks the 3' to 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC50= 12 μM) and induces G2 arrest in vitro.
- CAS number
1198097-97-0
- Purity
> 99%
- Form
Solid
- Molecular weight
220.25 Da
- Molecular formula
C10H8N2O2S
- PubChem identifier
1206243
- Nature
Synthetic
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MW 220.25 Da, Purity >99%. Mre11-Rad50-Nbs1 (MRN)-ATM complex inhibitor that blocks the 3' to 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC50= 12 μM) and induces G2 arrest in vitro.
Key facts
- CAS number
1198097-97-0
- Purity
> 99%
- Form
Solid
- Molecular weight
220.25 Da
- Molecular formula
C10H8N2O2S
- PubChem identifier
1206243
- Nature
Synthetic
- Biochemical name
Z-5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one
- Biological description
Mre11-Rad50-Nbs1 (MRN)-ATM complex inhibitor that blocks the 3' to 5' exonuclease activity associated with Mre11. Prevents ATM activation in response to double strand breaks (IC50= 12 μM) and induces G2 arrest in vitro.
- Canonical SMILES
C1=CC(=CC=C1C=C2C(=O)N=C(S2)N)O
- Isomeric SMILES
C1=CC(=CC=C1/C=C\2/C(=O)N=C(S2)N)O
- InChI
InChI=1S/C10H8N2O2S/c11-10-12-9(14)8(15-10)5-6-1-3-7(13)4-2-6/h1-5,13H,(H2,11,12,14)/b8-5-
- InChIKey
YBHQCJILTOVLHD-YVMONPNESA-N
- IUPAC name
(5Z)-2-amino-5-[(4-hydroxyphenyl)methylidene]-1,3-thiazol-4-one
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
+4°C
- Storage information
The product can be stored for up to 12 months
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