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AB143667

Mivacurium chloride, nicotinic acetylcholine antagonist

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(1 Publication)

MW 1100.2 Da, Purity >98%. Competitive nicotinic acetylcholine antagonist. Short-acting non-depolarizing neuromuscular transmission blocker. Reversibly inhibits 5-HT3A receptors. Shows muscle relaxant effects in vivo. .
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Chemical Structure - Mivacurium chloride, nicotinic acetylcholine antagonist (AB143667)
  • Chemical Structure

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Chemical Structure - Mivacurium chloride, nicotinic acetylcholine antagonist (AB143667)

2D chemical structure image of ab143667, Mivacurium chloride, nicotinic acetylcholine antagonist

Key facts

CAS number

106861-44-3

Purity

>98%

Form

Solid

form

Molecular weight

1100.2 Da

Molecular formula

C<sub>5</sub><sub>8</sub>H<sub>8</sub><sub>0</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>1</sub><sub>4</sub>

PubChem

5281080

Nature

Synthetic

Solubility

Soluble in water

Biochemical name

Mivacurium chloride

Biological description

Competitive nicotinic acetylcholine antagonist. Short-acting non-depolarizing neuromuscular transmission blocker. Reversibly inhibits 5-HT3A receptors. Shows muscle relaxant effects in vivo.

Canonical smiles

C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)CCCOC(=O)CCC=CCCC(=O)OCCC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)C.[Cl-].[Cl-]

Isomeric smiles

C[N+]1(CCC2=CC(=C(C=C2[C@H]1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)CCCOC(=O)CC/C=C/CCC(=O)OCCC[N+]4(CCC5=CC(=C(C=C5[C@H]4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)C.[Cl-].[Cl-]

InChi

InChI=1S/C58H80N2O14.2ClH/c1-59(25-21-41-35-47(63-3)49(65-5)37-43(41)45(59)29-39-31-51(67-7)57(71-11)52(32-39)68-8)23-17-27-73-55(61)19-15-13-14-16-20-56(62)74-28-18-24-60(2)26-22-42-36-48(64-4)50(66-6)38-44(42)46(60)30-40-33-53(69-9)58(72-12)54(34-40)70-10;;/h13-14,31-38,45-46H,15-30H2,1-12H3;2*1H/q+2;;/p-2/b14-13+;;/t45-,46-,59?,60?;;/m1../s1

InChiKey

WMSYWJSZGVOIJW-ONUALHDOSA-L

IUPAC Name

bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate;dichloride

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Complementary Products

Biochemicals

AB120296

Tunicamycin, Protein glycosylation inhibitor

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Proteins & Peptides

AB103506

Recombinant Human LC3B protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human LC3B protein (His tag N-Terminus) (AB103506)

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Primary Antibodies

AB168338

Anti-CLPX antibody [EP8772]

RabMAb|Recombinant|Trial Size

Immunocytochemistry/ Immunofluorescence - Anti-CLPX antibody [EP8772] (AB168338)

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Primary Antibodies

AB122897

Anti-ATF6 antibody [1-7]

KO Validated

Western blot - Anti-ATF6 antibody [1-7] (AB122897)

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Toxic, refer to SDS for further information.

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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Current biology : CB 31:3743-3754.e5 PubMed34270947

2021

Myelination induces axonal hotspots of synaptic vesicle fusion that promote sheath growth.

Applications

Unspecified application

Species

Unspecified reactive species

Rafael G Almeida,Jill M Williamson,Megan E Madden,Jason J Early,Matthew G Voas,William S Talbot,Isaac H Bianco,David A Lyons
View all publications
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