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AB146439

MK 212 hydrochloride, 5-HT2C receptor agonist

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MW 235.11 Da, Purity >99%. Potent, selective 5-HT2C receptor agonist (IC50 values are 28 and 420 nM for 5-HT2C and 5-HT2A receptors, respectively). Shows anxiogenic effects and decreases locomotor activity *in vivo.*.
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Chemical Structure - MK 212 hydrochloride, 5-HT2C receptor agonist (AB146439)
  • Chemical Structure

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Chemical Structure - MK 212 hydrochloride, 5-HT2C receptor agonist (AB146439)

2D chemical structure image of ab146439, MK 212 hydrochloride, 5-HT2C receptor agonist

Key facts

CAS number

61655-58-1

Purity

>99%

Form

Solid

form

Molecular weight

235.11 Da

Molecular formula

C<sub>8</sub>H<sub>1</sub><sub>2</sub>Cl<sub>2</sub>N<sub>4</sub>

PubChem

198421

Nature

Synthetic

Solubility

Soluble in water to 50 mM

Biochemical name

MK-212 hydrochloride

Biological description

Potent, selective 5-HT2C receptor agonist (IC50 values are 28 and 420 nM for 5-HT2C and 5-HT2A receptors, respectively). Shows anxiogenic effects and decreases locomotor activity *in vivo.*

Canonical smiles

C1CN(CCN1)C2=CN=CC(=N2)Cl.Cl

InChi

InChI=1S/C8H11ClN4.ClH/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13;/h5-6,10H,1-4H2;1H

InChiKey

PFIZGLUIYAZQFU-UHFFFAOYSA-N

IUPAC Name

2-chloro-6-piperazin-1-ylpyrazine;hydrochloride

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Biochemicals

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Biochemicals

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
The product can be stored for up to 12 months
Handling instructions

Need more advice on solubility, usage and handling? Please visit our our product support page for more details.

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Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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Toxic, refer to SDS for further information.

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Product protocols

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Product promise

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