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AB235508

MLN2480, pan-Raf kinase inhibitor

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MW 506.3 Da, Purity >98%. Selective pan-Raf kinase inhibitor. Orally active. Achieve your results faster with highly validated, pure and trusted compounds.

Key facts

CAS number

1096708-71-2

Purity

>98%

Form

Solid

form

Molecular weight

506.3 Da

Molecular formula

C<sub>1</sub><sub>7</sub>H<sub>1</sub><sub>2</sub>Cl<sub>2</sub>F<sub>3</sub>N<sub>7</sub>O<sub>2</sub>S

PubChem

25161177

Nature

Synthetic

Biochemical name

(r)-2-(1-(6-Amino-5-chloropyrimidine-4-carboxamido)ethyl)-n-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide

Biological description

Selective pan-Raf kinase inhibitor. Orally active.

Canonical smiles

CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl

Isomeric smiles

C[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl

InChi

InChI=1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(H,24,29,30)/t6-/m1/s1

InChiKey

VWMJHAFYPMOMGF-ZCFIWIBFSA-N

IUPAC Name

2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)pyridin-2-yl]-1,3-thiazole-5-carboxamide

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called B1706 MLN2480. B1706-25 is the same size as the 25 mg size of ab235508.

Protect from air and light.

Soluble in DMSO.

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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark|Store under desiccating conditions
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Product protocols

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Product promise

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