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MW 506.3 Da, Purity >98%. Selective pan-Raf kinase inhibitor. Orally active. Achieve your results faster with highly validated, pure and trusted compounds.

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Key facts

CAS number
1096708-71-2
Purity
> 98%
Form
Solid
Molecular weight
506.3 Da
Molecular formula
C17H12Cl2F3N7O2S
PubChem identifier
25161177
Nature
Synthetic

Target data

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MW 506.3 Da, Purity >98%. Selective pan-Raf kinase inhibitor. Orally active. Achieve your results faster with highly validated, pure and trusted compounds.

Key facts

Purity
> 98%
PubChem identifier
25161177
Biochemical name
(r)-2-(1-(6-Amino-5-chloropyrimidine-4-carboxamido)ethyl)-n-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide
Biological description

Selective pan-Raf kinase inhibitor. Orally active.

Canonical SMILES
CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
Isomeric SMILES
C[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
InChI
InChI=1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(H,24,29,30)/t6-/m1/s1
InChIKey
VWMJHAFYPMOMGF-ZCFIWIBFSA-N
IUPAC name
2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)pyridin-2-yl]-1,3-thiazole-5-carboxamide

Storage

Shipped at conditions
Blue Ice
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark, Store under desiccating conditions

Notes

This product is manufactured by BioVision, an Abcam company and was previously called B1706 MLN2480. B1706-25 is the same size as the 25 mg size of ab235508.

Protect from air and light.

Soluble in DMSO.

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