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AB141508

MM 11253, RARgamma

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(1 Publication)

MW 462.66 g/mol, Purity >98%. Selective RARγ antagonist. Blocks the growth inhibitory effects of RARγ-selective agonists. Shows antiapoptotic effects.
1 Images
Chemical Structure - MM 11253, RARgamma (AB141508)
  • Chemical Structure

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Chemical Structure - MM 11253, RARgamma (AB141508)

2D chemical structure image of ab141508, MM 11253, RARgamma

Key facts

CAS number

345952-44-5

Purity

>98%

Form

Solid

form

Molecular weight

462.66 g/mol

Molecular formula

C<sub>2</sub><sub>8</sub>H<sub>3</sub><sub>0</sub>O<sub>2</sub>S<sub>2</sub>

Nature

Synthetic

Solubility

Soluble in DMSO to 100 mM

Biological description

Selective RARγ antagonist. Blocks the growth inhibitory effects of RARγ-selective agonists. Shows antiapoptotic effects.

Canonical smiles

O=C(O)C1CCC2CC(CCC2C1)C3(SCCS3)C4CCC5C(C4)C(C)(C)CCC5(C)C

InChi

InChI=1S/C28H30O2S2/c1-26(2)11-12-27(3,4)24-17-22(9-10-23(24)26)28(31-13-14-32-28)21-8-7-18-15-20(25(29)30)6-5-19(18)16-21/h5-10,15-17H,11-14H2,1-4H3,(H,29,30)

InChiKey

DPVGXUNWCVEIGT-UHFFFAOYSA-N

IUPAC Name

6-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dithiolan-2-yl]-2-naphthanenecarboxylic acid

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
Ambient
Appropriate long-term storage conditions
Ambient
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Neuropharmacology 163:107657 PubMed31170403

2019

Retinoic acid receptor gamma is targeted by microRNA-124 and inhibits neurite outgrowth.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaohong Su,Xi Gu,Zhiduo Zhang,Weipeng Li,Xuemin Wang
View all publications
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