MMPSI, Caspase-3/7 Inhibitor I, caspase 3 and 7 inhibitor
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(4 Publications)
MW 324.35 Da, Purity >98%. Selective caspase 3 and 7 inhibitor (IC50 = 1.7 μM, caspase-3). Reduces ischemic-induced apoptosis (IC50 = 0.5 μM). Shows cardioprotective effects.
View Alternative Names
A830040C14Rik, APAF-3, APOPAIN, Apoptosis related cysteine peptidase, Apoptotic protease Mch-3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP3_HUMAN, CASP7_HUMAN, CASP9_HUMAN, CC3, CMH-1, CPP-32, CPP32B, Casp3a, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase 7, Caspase 7 apoptosis related cysteine peptidase, Caspase 9 Dominant Negative, Caspase 9 apoptosis related cysteine peptidase, Caspase 9c, Caspase-3, Caspase-3 subunit p12, Caspase-7 subunit p11, Caspase-9, Caspase-9 subunit p10, Cysteine protease CPP32, EC 3.4.22.56, ICE-LAP3, ICE-LAP6, ICE-like apoptotic protease 3, ICE-like apoptotic protease 6, ICE3, LICE, LICE2, MCH3, MCH6, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, PARP cleavage protease, PPP1R56, Procaspase3, Protein Yama, RNCASP9, SCA-1, SREBP cleavage activity 1, Yama, Yama protein, mldy, protein phosphatase 1, regulatory subunit 56
- Chemical Structure
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Chemical Structure - MMPSI, Caspase-3/7 Inhibitor I, caspase 3 and 7 inhibitor (AB145046)
2D chemical structure image of ab145046, MMPSI, Caspase-3/7 Inhibitor I, caspase 3 and 7 inhibitor
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Publications (4)
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Journal of biochemical and molecular toxicology 39:e70105 PubMed40067291
2025
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Immunity, inflammation and disease 11:e1102 PubMed38156384
2024
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iScience 26:107348 PubMed37554442
2023
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Acta biochimica Polonica 69:91-100 PubMed35143137
2022
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