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AB287129

Monochlorobimane

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MW 226.66 Da, Purity >98%. Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nm.

Key facts

CAS number

76421-73-3

Purity

>98%

Form

Solid

form

Molecular weight

226.66 Da

Molecular formula

C<sub>1</sub><sub>0</sub>H<sub>1</sub><sub>1</sub>ClN<sub>2</sub>O<sub>2</sub>

PubChem

114886

Nature

Synthetic

Solubility

DMSO

Biochemical name

Monochlorobimane

Biological description

Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nm.

Canonical smiles

CC1=C(N2C(=C(C(=O)N2C1=O)C)CCl)C

InChi

InChI=1S/C10H11ClN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3

InChiKey

SUIPVTCEECPFIB-UHFFFAOYSA-N

IUPAC Name

7-(chloromethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione

Excitation/Emission

Ex: 394nm, Em: 490nm

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called B2671 Monochlorobimane. B2671-5 is the same size as the 5 mg size of ab287129.
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Properties and storage information

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark
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Product protocols

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