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MW 226.66 Da, Purity >=98%. Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nm.

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Key facts

CAS number
76421-73-3
Purity
>= 98%
Form
Solid
Molecular weight
226.66 Da
Molecular formula
C10H11ClN2O2
PubChem identifier
114886
Nature
Synthetic
Excitation/Emission
Ex: 394nm, Em: 490nm

Target data

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MW 226.66 Da, Purity >=98%. Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nm.

Key facts

Purity
>= 98%
PubChem identifier
114886
Solubility

DMSO.

Biochemical name
Monochlorobimane
Biological description

Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nm.

Canonical SMILES
CC1=C(N2C(=C(C(=O)N2C1=O)C)CCl)C
InChI
InChI=1S/C10H11ClN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3
InChIKey
SUIPVTCEECPFIB-UHFFFAOYSA-N
IUPAC name
7-(chloromethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione
Excitation/Emission
Ex: 394nm, Em: 490nm

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store in the dark

Notes

This product is manufactured by BioVision, an Abcam company and was previously called B2671 Monochlorobimane. B2671-5 is the same size as the 5 mg size of ab287129.

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