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AB144305

Monosodium urate, Pro-inflammatory agent

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(1 Publication)

MW 190.09 Da. NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo.
1 Images
Chemical Structure - Monosodium urate, Pro-inflammatory agent (AB144305)
  • Chemical Structure

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Chemical Structure - Monosodium urate, Pro-inflammatory agent (AB144305)

2D chemical structure image of ab144305, Monosodium urate, Pro-inflammatory agent

Key facts

CAS number

1198-77-2

Molecular weight

190.09 Da

Molecular formula

C<sub>5</sub>H<sub>3</sub>N<sub>4</sub>NaO<sub>3</sub>

PubChem

23697816

Nature

Synthetic

Solubility

Soluble in 1 N NaOH to 25 mM

Biochemical name

Sodium urate

Biological description

NLRP3/NALP3 inflammasome activator. Stimulates caspase-1 activating NLRP3/NALP3 inflammasome, results in active IL-1β and IL-18 production. Active in vitro and in vivo.

Canonical smiles

C12=C(NC(=O)NC1=O)[N-]C(=O)N2.[Na+]

InChi

InChI=1S/C5H4N4O3.Na/c10-3-1-2(7-4(11)6-1)8-5(12)9-3;/h(H4,6,7,8,9,10,11,12);/q;+1/p-1

InChiKey

NAFSTSRULRIERK-UHFFFAOYSA-M

IUPAC Name

sodium;3,7-dihydropurin-9-ide-2,6,8-trione

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Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB87199

Anti-Muscarinic Acetylcholine Receptor M3/CHRM3 antibody

BOND RX™ Validated

Western blot - Anti-Muscarinic Acetylcholine Receptor M3/CHRM3 antibody (AB87199)

  • 1
  • 1
Primary Antibodies

AB72625

Anti-TRA2A antibody

Western blot - Anti-TRA2A antibody (AB72625)

  • 5
  • 1
Primary Antibodies

AB235094

Anti-Bile Acid Receptor NR1H4 antibody

Western blot - Anti-Bile Acid Receptor NR1H4 antibody (AB235094)

  • 0
  • 0
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

RNA biology 17:335-349 PubMed31840571

2019

NLRP3 inflammasome activation by Foot-and-mouth disease virus infection mainly induced by viral RNA and non-structural protein 2B.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoying Zhi,Yun Zhang,Shiqi Sun,Zhihui Zhang,Hu Dong,Xin Luo,Yanquan Wei,Zengjun Lu,Yongxi Dou,Run Wu,Zhengfan Jiang,Changjiang Weng,Ho Seong Seo,Huichen Guo
View all publications
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Product promise

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