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MW 460.27 Da, Purity >98%. Potent, selective, competitive P2Y1 antagonist (Ki = 100 nM). Inhibits ATP induced glutamate release *in vitro* and inhibits ADP ability to evoke platelet shape change and aggregation.

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Images

Chemical Structure - MRS 2179, P2Y1 antagonist (AB120414), expandable thumbnail

Publications

Key facts

CAS number

101204-49-3

Purity

> 98%

Form

Solid

Molecular weight

460.27 Da

Molecular formula

C11H22N6O10P2

PubChem identifier

71308613

Nature

Synthetic

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MW 460.27 Da, Purity >98%. Potent, selective, competitive P2Y1 antagonist (Ki = 100 nM). Inhibits ATP induced glutamate release *in vitro* and inhibits ADP ability to evoke platelet shape change and aggregation.

Key facts

Purity

> 98%

PubChem identifier

71308613

Solubility

Soluble in water to 100 mM.

Biochemical name

MRS 2179 ammonium salt hydrate, >=98% (HPLC)

Biological description

Potent, selective, competitive P2Y1 antagonist (Ki = 100 nM). Inhibits ATP induced glutamate release *in vitro* and inhibits ADP ability to evoke platelet shape change and aggregation.

Canonical SMILES

CNC1=C2C(=NC=N1)N(C=N2)C3CC(C(O3)COP(=O)(O)O)OP(=O)(O)O.N.O

Isomeric SMILES

CNC1=C2C(=NC=N1)N(C=N2)[C@H]3C[C@@H]([C@H](O3)COP(=O)(O)O)OP(=O)(O)O.N.O

InChI

InChI=1S/C11H17N5O9P2.H3N.H2O/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(25-27(20,21)22)7(24-8)3-23-26(17,18)19;;/h4-8H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22);1H3;1H2/t6-,7+,8+;;/m0../s1

InChIKey

DEQIORFOBOEGKZ-ZJWYQBPBSA-N

IUPAC name

azane;[(2R,3S,5R)-5-[6-(methylamino)purin-9-yl]-2-(phosphonooxymethyl)oxolan-3-yl] dihydrogen phosphate;hydrate

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - MRS 2179, P2Y1 antagonist (ab120414), expandable thumbnail

    Chemical Structure - MRS 2179, P2Y1 antagonist (ab120414)

    2D chemical structure image of ab120414, MRS 2179, P2Y1 antagonist

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Product protocols

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