Products
Sample Prep & Detection Kits
Conjugation kitsPurification kitsSample preparation kitsChromogen kitsIHC kitsChIP kitsAccessory Reagents & Controls
Accessory reagents & controlsBiochemicals
BiochemicalsProteins and Peptides
Proteins and peptidesOur latest ELISA kit: Human Tau (phospho T217) - Intracellular
Highly sensitive kit offering the most promising biomarkers for Alzheimer’s disease diagnostics. Learn about all product ranges with our product overviews.
Resources
Featured events
Make new connections at our global events.
Support
Our programs
New Lab Program
Get a head start with our exclusive new lab discount. Enjoy 20% off and free shipping for three months.
New Biotech Program
Just starting out? Get 15% off and free shipping to your lab for six months.
Product promise
Peace of mind that all products perform as stated.
Product reviews
Leave reviews, get rewarded and help your community.
Trial program
Try untested species and applications to earn money off your next order.
MW 236.72 Da, Purity >99%. Brain penetrant, potent, selective and non-competitive mGlu5 receptor antagonist (IC50 = 5 nM in Ca2+-flux assay; Ki = 16 nM). In vivo anxiolytic, devoid of side effects seen with MPEP and benzodiazepines.
Soluble in 1 ml water to give specified mM/ml concentration.
Alternative names=GLUR, Smp_128940
- CAS number
1186195-60-7
- Purity
> 99%
- Form
Solid
- Molecular weight
236.72 Da
- Molecular formula
C11H9ClN2S
- PubChem identifier
45073467
- Nature
Synthetic
Images
Recommended products
MW 236.72 Da, Purity >99%. Brain penetrant, potent, selective and non-competitive mGlu5 receptor antagonist (IC50 = 5 nM in Ca2+-flux assay; Ki = 16 nM). In vivo anxiolytic, devoid of side effects seen with MPEP and benzodiazepines.
Soluble in 1 ml water to give specified mM/ml concentration.
Alternative names=GLUR, Smp_128940
Key facts
- CAS number
1186195-60-7
- Purity
> 99%
- Form
Solid
- Molecular weight
236.72 Da
- Molecular formula
C11H9ClN2S
- PubChem identifier
45073467
- Nature
Synthetic
- Biochemical name
MTEP hydrochloride
- Biological description
Brain penetrant, potent, selective and non-competitive mGlu5 receptor antagonist (IC50 = 5 nM in Ca2+-flux assay; Ki = 16 nM). In vivo anxiolytic, devoid of side effects seen with MPEP and benzodiazepines.
Soluble in 1 ml water to give specified mM/ml concentration.- Canonical SMILES
CC1=NC(=CS1)C#CC2=CN=CC=C2.Cl
- InChI
InChI=1S/C11H8N2S.ClH/c1-9-13-11(8-14-9)5-4-10-3-2-6-12-7-10;/h2-3,6-8H,1H3;1H
- InChIKey
YCIOJDKGCWAHLR-UHFFFAOYSA-N
- IUPAC name
2-methyl-4-(2-pyridin-3-ylethynyl)-1,3-thiazole;hydrochloride
Storage
- Shipped at conditions
Ambient - Can Ship with Ice
- Appropriate long-term storage conditions
+4°C
- Storage information
Store under desiccating conditions, The product can be stored for up to 12 months
Product promise
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com