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AB141616

N-Acetyl-S-farnesyl-L-cysteine (AFC), Specific S-farnesylcysteine methyl transferase inhibitor

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MW 367.5 Da, Purity >98%. Specific S-farnesylcysteine methyl transferase inhibitor (Km= 20 μM). Modulator of G protein and G protein coupled receptor signaling. Inhibits neutrophil chemotaxis and other inflammatory responses in vitro. Topically inhibits acute inflammation in vivo.
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Chemical Structure - N-Acetyl-S-farnesyl-L-cysteine (AFC), Specific S-farnesylcysteine methyl transferase inhibitor (AB141616)
  • Chemical Structure

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Chemical Structure - N-Acetyl-S-farnesyl-L-cysteine (AFC), Specific S-farnesylcysteine methyl transferase inhibitor (AB141616)

2D chemical structure image of ab141616, N-Acetyl-S-farnesyl-L-cysteine (AFC), Specific S-farnesylcysteine methyl transferase inhibitor

Key facts

Purity

>98%

Form

Liquid

form

Molecular weight

367.5 Da

Molecular formula

C<sub>2</sub><sub>0</sub>H<sub>3</sub><sub>3</sub>NO<sub>3</sub>S

PubChem

1994

Nature

Synthetic

Biochemical name

L-Cysteine,N-acetyl-S-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-

Biological description

Specific S-farnesylcysteine methyl transferase inhibitor (Km= 20 μM). Modulator of G protein and G protein coupled receptor signaling. Inhibits neutrophil chemotaxis and other inflammatory responses in vitro. Topically inhibits acute inflammation in vivo.

Canonical smiles

CC(=CCCC(=CCCC(=CCSCC(C(=O)O)NC(=O)C)C)C)C

InChi

InChI=1S/C20H33NO3S/c1-15(2)8-6-9-16(3)10-7-11-17(4)12-13-25-14-19(20(23)24)21-18(5)22/h8,10,12,19H,6-7,9,11,13-14H2,1-5H3,(H,21,22)(H,23,24)

InChiKey

XTURYZYJYQRJDO-UHFFFAOYSA-N

IUPAC Name

2-acetamido-3-(3,7,11-trimethyldodeca-2,6,10-trienylsulfanyl)propanoic acid

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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