MW 930.4 g/mol, Purity >98%. Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity.
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Key facts
- CAS number
- 108321-22-8
- Purity
- > 98%
- Molecular weight
- 930.4 g/mol
- Molecular formula
- C53H104NO9P
- Nature
- Synthetic
Recommended products
MW 930.4 g/mol, Purity >98%. Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity.
Key facts
- CAS number
- 108321-22-8
- Purity
- > 98%
- Molecular weight
- 930.4 g/mol
- Molecular formula
- C53H104NO9P
- Nature
- Synthetic
- Biological description
Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity.
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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1 product image
Chemical Structure - N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone (ab145219)
2D chemical structure image of ab145219, N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone
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