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MW 177.24 Da, Purity >98%. Cell permeable free radicle trap. Inhibits LPS-induced NF-κB DNA binding activity, inhibits COX-2 catalytic activity and inhibits lipid peroxidation in rat liver microsomes. Blocks indiction of iNOS by reactive oxygen species.

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Images

Chemical Structure - N-tert-Butyl-alpha-phenylnitrone (PBN) (AB146814), expandable thumbnail

Key facts

CAS number
3376-24-7
Purity
> 98%
Form
Solid
Molecular weight
177.24 Da
Molecular formula
C11H15NO
PubChem identifier
638877
Nature
Synthetic

Target data

Recommended products

MW 177.24 Da, Purity >98%. Cell permeable free radicle trap. Inhibits LPS-induced NF-κB DNA binding activity, inhibits COX-2 catalytic activity and inhibits lipid peroxidation in rat liver microsomes. Blocks indiction of iNOS by reactive oxygen species.

Key facts

Purity
> 98%
PubChem identifier
638877
Solubility

Soluble in DMSO to 50 mM.

Biochemical name
n-Tert-butyl-alpha-phenylnitrone
Biological description

Cell permeable free radicle trap. Inhibits LPS-induced NF-κB DNA binding activity, inhibits COX-2 catalytic activity and inhibits lipid peroxidation in rat liver microsomes. Blocks indiction of iNOS by reactive oxygen species.

Canonical SMILES
CC(C)(C)[N+](=CC1=CC=CC=C1)[O-]
Isomeric SMILES
CC(C)(C)/[N+](=C/C1=CC=CC=C1)/[O-]
InChI
InChI=1S/C11H15NO/c1-11(2,3)12(13)9-10-7-5-4-6-8-10/h4-9H,1-3H3/b12-9-
InChIKey
IYSYLWYGCWTJSG-XFXZXTDPSA-N
IUPAC name
N-tert-butyl-1-phenylmethanimine oxide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions

Product promise

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1 product image

  • Chemical Structure - N-tert-Butyl-alpha-phenylnitrone (PBN) (ab146814), expandable thumbnail

    Chemical Structure - N-tert-Butyl-alpha-phenylnitrone (PBN) (ab146814)

    2D chemical structure image of ab146814, N-tert-Butyl-alpha-phenylnitrone (PBN)

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Product protocols

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