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MW 539.6 Da, Purity >97%. Broad spectrum, potent protease inhibitor (Ki = 95.3 pM). Inhibits NF-κB activation and complement activation. Selective for human tryptase.

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Images

Chemical Structure - Nafamostat Mesylate, Protease inhibitor (AB141432), expandable thumbnail

Publications

Key facts

CAS number

82956-11-4

Purity

> 97%

Form

Solid

Molecular weight

539.6 Da

Molecular formula

C21H25N5O8S2

PubChem identifier

5311180

Nature

Synthetic

Recommended products

MW 539.6 Da, Purity >97%. Broad spectrum, potent protease inhibitor (Ki = 95.3 pM). Inhibits NF-κB activation and complement activation. Selective for human tryptase.

Key facts

Purity

> 97%

PubChem identifier

5311180

Solubility

Soluble in DMSO to 100 mM. Soluble in water to 100 mM.

Biochemical name

Nafamostat mesylate

Biological description

Broad spectrum, potent protease inhibitor (Ki = 95.3 pM). Inhibits NF-κB activation and complement activation. Selective for human tryptase.

Canonical SMILES

CS(=O)(=O)O.CS(=O)(=O)O.C1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N

InChI

InChI=1S/C19H17N5O2.2CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;2*1-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);2*1H3,(H,2,3,4)

InChIKey

SRXKIZXIRHMPFW-UHFFFAOYSA-N

IUPAC name

(6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate;methanesulfonic acid

Storage

Shipped at conditions

Ambient - Can Ship with Ice

Appropriate short-term storage conditions

-20°C

Appropriate long-term storage conditions

-20°C

Storage information

Store under desiccating conditions, The product can be stored for up to 12 months

Product promise

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1 product image

  • Chemical Structure - Nafamostat Mesylate, Protease inhibitor (ab141432), expandable thumbnail

    Chemical Structure - Nafamostat Mesylate, Protease inhibitor (ab141432)

    2D chemical structure image of ab141432, Nafamostat Mesylate, Protease inhibitor

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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