JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB144312

Nargenicin A1, Antibiotic agent

Be the first to review this product! Submit a review

|

(0 Publication)

MW 515.6 Da, Purity >97%. Broad spectrum antibiotic agent. Potential anti-inflammatory agent. Active against Gram-positive bacteria, particularly Staphylococcus and Clostridia. Attenuates LPS-induced nitric oxide production in microglia. Suppresses IL-1β, TNF-α and iNOS production.
1 Images
Chemical Structure - Nargenicin A1, Antibiotic agent (AB144312)
  • Chemical Structure

Lab

Chemical Structure - Nargenicin A1, Antibiotic agent (AB144312)

2D chemical structure image of ab144312, Nargenicin A1, Antibiotic agent

Key facts

CAS number

70695-02-2

Purity

>97%

Form

Solid

form

Source

Actinomyces sp.

Molecular weight

515.6 Da

Molecular formula

C<sub>2</sub><sub>8</sub>H<sub>3</sub><sub>7</sub>NO<sub>8</sub>

PubChem

6326334

Nature

Native

Solubility

Soluble in DMSO to 25 mM

Biochemical name

Nargenicin A1

Biological description

Broad spectrum antibiotic agent. Potential anti-inflammatory agent. Active against Gram-positive bacteria, particularly Staphylococcus and Clostridia. Attenuates LPS-induced nitric oxide production in microglia. Suppresses IL-1β, TNF-α and iNOS production.

Canonical smiles

CC1C=C(C23C(CC(C(=O)OC1C(C)O)OC)C=CC4C2C(C(C(C4O3)OC(=O)C5=CC=CN5)C)O)C

Isomeric smiles

C[C@@H]1/C=C(/[C@]23[C@@H](C[C@@H](C(=O)O[C@@H]1[C@@H](C)O)OC)C=C[C@@H]4[C@H]2[C@@H]([C@H]([C@H]([C@@H]4O3)OC(=O)C5=CC=CN5)C)O)\C

InChi

InChI=1S/C28H37NO8/c1-13-11-14(2)28-17(12-20(34-5)27(33)35-23(13)16(4)30)8-9-18-21(28)22(31)15(3)24(25(18)37-28)36-26(32)19-7-6-10-29-19/h6-11,13,15-18,20-25,29-31H,12H2,1-5H3/b14-11+/t13-,15-,16-,17-,18-,20+,21+,22-,23+,24-,25-,28+/m1/s1

InChiKey

YEUSSARNQQYBKH-SIMZXIQRSA-N

IUPAC Name

[(1S,3R,4R,5R,6R,7S,8R,11S,13S,16S,17R,18E)-6-hydroxy-16-[(1R)-1-hydroxyethyl]-13-methoxy-5,17,19-trimethyl-14-oxo-2,15-dioxatetracyclo[9.8.0.01,7.03,8]nonadeca-9,18-dien-4-yl] 1H-pyrrole-2-carboxylate

style
left-column

Complementary Products

Primary Antibodies

AB35654

Anti-E. coli LPS antibody [2D7/1]

Immunocytochemistry/ Immunofluorescence - Anti-E. coli LPS antibody [2D7/1] (AB35654)

  • 4
  • 10
Primary Antibodies

AB80579

Anti-Tau antibody [TAU-5] - BSA and Azide free

Recombinant

Western blot - Anti-Tau antibody [TAU-5] - BSA and Azide free (AB80579)

  • 5
  • 6
Primary Antibodies

AB7321

Biotin Anti-bacterial Alkaline Phosphatase antibody

  • 0
  • 0
Primary Antibodies

AB137967

Anti-E. coli antibody

Immunocytochemistry/ Immunofluorescence - Anti-E. coli antibody (AB137967)

  • 5
  • 1
style
left-column
style
left-column

Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
style
left-column
style
left-column
style
left-column

Product protocols

style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com