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AB142132

Necrostatin-7, Necroptosis inhibitor

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MW 371.4 Da, Purity >98%. Necroptosis inhibitor. Structurally distinct from other necrostatins (Nec-1, Nec-3, Nec-4 and Nec-5).
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Chemical Structure - Necrostatin-7, Necroptosis inhibitor (AB142132)
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Chemical Structure - Necrostatin-7, Necroptosis inhibitor (AB142132)

2D chemical structure image of ab142132, Necrostatin-7, Necroptosis inhibitor

Key facts

CAS number

351062-08-3

Purity

>98%

Form

Solid

form

Molecular weight

371.4 Da

Molecular formula

C<sub>1</sub><sub>6</sub>H<sub>1</sub><sub>0</sub>FN<sub>5</sub>OS<sub>2</sub>

PubChem

1239801

Nature

Synthetic

Solubility

Soluble in DMSO

Soluble in ethanol

Biochemical name

Necrostatin-7

Biological description

Necroptosis inhibitor. Structurally distinct from other necrostatins (Nec-1, Nec-3, Nec-4 and Nec-5).

Canonical smiles

C1=CC(=CC=C1C2=C(C=NN2)C=C3C(=O)N(C(=N)S3)C4=NC=CS4)F

Isomeric smiles

C1=CC(=CC=C1C2=C(C=NN2)/C=C\3/C(=O)N(C(=N)S3)C4=NC=CS4)F

InChi

InChI=1S/C16H10FN5OS2/c17-11-3-1-9(2-4-11)13-10(8-20-21-13)7-12-14(23)22(15(18)25-12)16-19-5-6-24-16/h1-8,18H,(H,20,21)/b12-7-,18-15?

InChiKey

SMJGLNVGTJLIRV-KBEFMPHXSA-N

IUPAC Name

(5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one

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Complementary Products

Biochemicals

AB141053

Necrostatin-1, necroptosis inhibitor

Functional Studies - Necrostatin-1, necroptosis inhibitor (AB141053)

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Biochemicals

AB143839

Necrosulfonamide, necroptosis inhibitor

Chemical Structure - Necrosulfonamide, necroptosis inhibitor (AB143839)

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Assay Kits

AB115347

Live and Dead Cell Assay

Functional Studies - Live and Dead Cell Assay (AB115347)

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Biochemicals

AB254395

GSK872, Necroptosis inhibitor

Chemical Structure - GSK872, Necroptosis inhibitor (AB254395)

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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 1866 Necrostatin-7. 1866-25 is the same size as the 25 mg size of ab142132.
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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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Product promise

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