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MW 1133.3 Da, Purity >95%. Neurokinin A, Tachykinin peptide. Achieve your results faster with highly validated, pure and trusted compounds.

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Images

Chemical Structure - Neurokinin A, Tachykinin peptide (AB120185), expandable thumbnail
  • Functional Studies - Neurokinin A, Tachykinin peptide (AB120185), expandable thumbnail

Publications

Key facts

CAS number
86933-74-6
Purity
> 95%
Form
Solid
Molecular weight
1133.3 Da
Molecular formula
C50H80N14O14S
PubChem identifier
55582
Nature
Synthetic

Target data

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MW 1133.3 Da, Purity >95%. Neurokinin A, Tachykinin peptide. Achieve your results faster with highly validated, pure and trusted compounds.

Key facts

Purity
> 95%
PubChem identifier
55582
Solubility

Soluble in water.

Biochemical name
alpha-Neurokinin;Neuromedin L;Substance K
Canonical SMILES
CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CCCCN)NC(=O)C(CC2=CN=CN2)N
InChI
InChI=1S/C50H80N14O14S/c1-26(2)18-34(45(73)58-32(42(53)70)15-17-79-6)57-38(67)23-55-49(77)40(27(3)4)63-47(75)35(19-29-12-8-7-9-13-29)60-48(76)37(24-65)62-46(74)36(21-39(68)69)61-50(78)41(28(5)66)64-44(72)33(14-10-11-16-51)59-43(71)31(52)20-30-22-54-25-56-30/h7-9,12-13,22,25-28,31-37,40-41,65-66H,10-11,14-21,23-24,51-52H2,1-6H3,(H2,53,70)(H,54,56)(H,55,77)(H,57,67)(H,58,73)(H,59,71)(H,60,76)(H,61,78)(H,62,74)(H,63,75)(H,64,72)(H,68,69)
InChIKey
HEAUFJZALFKPBA-UHFFFAOYSA-N
IUPAC name
3-[[2-[[6-amino-2-[[2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[1-[[1-[[1-[[2-[[1-[(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions, The product can be stored for up to 12 months

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2 product images

  • Chemical Structure - Neurokinin A, Tachykinin peptide (ab120185), expandable thumbnail

    Chemical Structure - Neurokinin A, Tachykinin peptide (ab120185)

    2D chemical structure image of ab120185, Neurokinin A, Tachykinin peptide

  • Functional Studies - Neurokinin A, Tachykinin peptide (ab120185), expandable thumbnail

    Functional Studies - Neurokinin A, Tachykinin peptide (ab120185)

    K562 cells were incubated at 37°C for 4h with vehicle control (0 μM) and 15 nM of neurokinin A (ab120185). Increased expression of p53 (Anti-p53 antibody [PAb 240] ab26) correlates with an increase in neurokinin A concentration, as described in literature.

    Whole cell lysates were prepared with RIPA buffer (containing protease inhibitors and sodium orthovanadate), 20 μg of each were loaded on the gel and the WB was run under reducing conditions. After transfer the membrane was blocked for an hour using 3% milk before being incubated with Anti-p53 antibody [PAb 240] ab26 at 5 μg/ml and Anti-beta Actin antibody ab8227 at 1 μg/ml overnight at 4°C. Antibody binding was detected using an anti-mouse antibody conjugated to HRP (Goat Anti-Mouse IgG H&L (HRP) preadsorbed ab97040) at 1/10000 dilution and visualised using ECL development solution.

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