MW 2210.52 g/mol. Endogenous ligand for the NPS receptor involved in many biological functions including sleeping/wakening, locomotion, anxiety, and food intake.
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Key facts
- CAS number
- 412938-75-1
- Form
- Solid
- Molecular weight
- 2210.52 g/mol
- Nature
- Synthetic
Recommended products
MW 2210.52 g/mol. Endogenous ligand for the NPS receptor involved in many biological functions including sleeping/wakening, locomotion, anxiety, and food intake.
Key facts
- CAS number
- 412938-75-1
- Form
- Solid
- Molecular weight
- 2210.52 g/mol
- Nature
- Synthetic
- Solubility
Soluble in Water.
- Biological description
Endogenous ligand for the NPS receptor involved in many biological functions including sleeping/wakening, locomotion, anxiety, and food intake.
Storage
- Shipped at conditions
- Ambient - Can Ship with Ice
- Appropriate short-term storage conditions
- -20°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Store under desiccating conditions, The product can be stored for up to 12 months
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2 product images
Chemical Structure - Neuropeptide S (rat), NPS receptor agonist (ab120246)
2D chemical structure image of ab120246, Neuropeptide S (rat), NPS receptor agonist
Functional Studies - Neuropeptide S (rat), NPS receptor agonist (ab120246)
ab70280 staining cAMP in HEK293 cells treated with neuropeptide S (ab120246), by ICC/IF. Increase in cAMP expression correlates with increased concentration of neuropeptide S, as described in literature.
The cells were incubated at 37°C for 10 minutes in media containing different concentrations of ab120246 (neuropeptide S) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab70280 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight 488 goat anti-mouse polyclonal antibody (Goat Anti-Mouse IgG H&L (DyLight® 488) preadsorbed ab96879) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.
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