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AB120246

Neuropeptide S (rat), NPS receptor agonist

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MW 2210.52 g/mol. Endogenous ligand for the NPS receptor involved in many biological functions including sleeping/wakening, locomotion, anxiety, and food intake.
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Functional Studies - Neuropeptide S (rat), NPS receptor agonist (AB120246)
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Unknown

Functional Studies - Neuropeptide S (rat), NPS receptor agonist (AB120246)

ab70280 staining cAMP in HEK293 cells treated with neuropeptide S (ab120246), by ICC/IF. Increase in cAMP expression correlates with increased concentration of neuropeptide S, as described in literature.
The cells were incubated at 37°C for 10 minutes in media containing different concentrations of ab120246 (neuropeptide S) in DMSO, fixed with 100% methanol for 5 minutes at -20°C and blocked with PBS containing 10% goat serum, 0.3 M glycine, 1% BSA and 0.1% tween for 2h at room temperature. Staining of the treated cells with ab70280 (5 µg/ml) was performed overnight at 4°C in PBS containing 1% BSA and 0.1% tween. A DyLight® 488 goat anti-mouse polyclonal antibody (ab96879) at 1/250 dilution was used as the secondary antibody. Nuclei were counterstained with DAPI and are shown in blue.

Chemical Structure - Neuropeptide S (rat), NPS receptor agonist (AB120246)
  • Chemical Structure

Lab

Chemical Structure - Neuropeptide S (rat), NPS receptor agonist (AB120246)

2D chemical structure image of ab120246, Neuropeptide S (rat), NPS receptor agonist

Key facts

CAS number

412938-75-1

Form

Solid

form

Molecular weight

2210.52 g/mol

Nature

Synthetic

Solubility

Soluble in Water

Biological description

Endogenous ligand for the NPS receptor involved in many biological functions including sleeping/wakening, locomotion, anxiety, and food intake.

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Properties and storage information

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
Store under desiccating conditions|The product can be stored for up to 12 months
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Product protocols

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