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MW 524.6 Da, Purity >99%. Potent, selective CaMK III inhibitor (IC50 = 60 nM). Histidine protein kinase inhibitor (IC50 = 6.6 μM). Induces G1/S cell cycle arrest and apoptosis. Shows anticancer effects. Antibacterial agent in vivo. .

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Images

Chemical Structure - NH 125, CaMK III inhibitor (AB145188), expandable thumbnail

Key facts

CAS number
278603-08-0
Purity
> 99%
Form
Solid
Molecular weight
524.6 Da
Molecular formula
C27H45IN2
PubChem identifier
10436839
Nature
Synthetic

Target data

Recommended products

MW 524.6 Da, Purity >99%. Potent, selective CaMK III inhibitor (IC50 = 60 nM). Histidine protein kinase inhibitor (IC50 = 6.6 μM). Induces G1/S cell cycle arrest and apoptosis. Shows anticancer effects. Antibacterial agent in vivo. .

Key facts

Purity
> 99%
PubChem identifier
10436839
Solubility

Soluble in ethanol to 100 mM.

Soluble in DMSO to 100 mM.

Biochemical name
1-Benzyl-3-cetyl-2-methylimidazolium iodide
Biological description

Potent, selective CaMK III inhibitor (IC50 = 60 nM). Histidine protein kinase inhibitor (IC50 = 6.6 μM). Induces G1/S cell cycle arrest and apoptosis. Shows anticancer effects. Antibacterial agent in vivo.

Canonical SMILES
CCCCCCCCCCCCCCCCN1C=C[N+](=C1C)CC2=CC=CC=C2.[I-]
InChI
InChI=1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1
InChIKey
RVWOHCBHAGBLLT-UHFFFAOYSA-M
IUPAC name
1-benzyl-3-hexadecyl-2-methylimidazol-1-ium;iodide

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
Storage information
It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions

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1 product image

  • Chemical Structure - NH 125, CaMK III inhibitor (ab145188), expandable thumbnail

    Chemical Structure - NH 125, CaMK III inhibitor (ab145188)

    2D chemical structure image of ab145188, NH 125, CaMK III inhibitor

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Product protocols

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