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MW 301.32 Da, Purity >98%. Microtubule inhibitor. Rapidly depolymerises microtubules in vivo and inhibits tubulin polymerisation in vitro. Inhibits mitosis. Also reduces stem cell pluripotency factors Oct 4 and Nanog.

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Images

Chemical Structure - Nocodazole, Microtubule inhibitor (AB120630), expandable thumbnail
  • Immunoprecipitation - Nocodazole, Microtubule inhibitor (AB120630), expandable thumbnail

Publications

Key facts

CAS number
31430-18-9
Purity
> 98%
Form
Solid
Molecular weight
301.32 Da
Molecular formula
C14H11N3O3S
PubChem identifier
4122
Nature
Synthetic

Alternative names

Recommended products

MW 301.32 Da, Purity >98%. Microtubule inhibitor. Rapidly depolymerises microtubules in vivo and inhibits tubulin polymerisation in vitro. Inhibits mitosis. Also reduces stem cell pluripotency factors Oct 4 and Nanog.

Key facts

Purity
> 98%
PubChem identifier
4122
Solubility

Soluble in DMSO to 50 mM.

Biochemical name
Nocodazole
Biological description

Microtubule inhibitor. Rapidly depolymerises microtubules in vivo and inhibits tubulin polymerisation in vitro. Inhibits mitosis. Also reduces stem cell pluripotency factors Oct 4 and Nanog.

Canonical SMILES
COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
InChI
InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)
InChIKey
KYRVNWMVYQXFEU-UHFFFAOYSA-N
IUPAC name
methyl N-[6-(thiophene-2-carbonyl)-1H-benzimidazol-2-yl]carbamate

Storage

Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months

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Product protocols

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